Department of Obstetrics and Gynecology, Meir Medical Center, 59 Tchernichovsky St., 4428164, Kfar Saba, Israel.
Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
BMC Womens Health. 2023 Mar 10;23(1):99. doi: 10.1186/s12905-023-02233-2.
Delayed-onset postpartum preeclampsia (PET) is defined as a new diagnosis of preeclampsia presenting 48 h to 6 weeks postpartum. This disorder is infrequent and associated with a higher incidence of complications as compared to antepartum PET. There seems to be a need to further characterize this disorder. The aim of the study was to investigate the difference of maternal heart rate in women with delayed onset postpartum preeclampsia as compared to healthy controls.
The medical files of all women who were readmitted with delayed onset postpartum preeclampsia during 2014-2020 were reviewed. Data on maternal physiological characteristics were compared to healthy control group of women at the same post-partum day, with uncomplicated pregnancies.
Included 45 women with the diagnosis of delayed onset of preeclampsia at 6.3 ± 2.86 post-partum day. As compared to controls (n = 49), women with delayed post-partum were older, 34.6 ± 5.4 vs. 32.3 ± 4.7 years, p = 0.003. There were no differences between groups regarding maternal gravidity, parity, BMI (kg/m) or Hb level at delivery day. Women with delayed post-partum preeclampsia had lower mean pulse rate as compared to controls, 58 ± 15 bpm vs. 83 ± 11.6 bpm, respectively, P < 0.0001. Only 17% of the women in the delayed onset group had pulse rate above 70 bpm as compared to 83% in the control group.
Maternal low heart rate in cases with delayed onset of post-partum preeclampsia is an important clinical characteristic that may reflect baroreceptors response to maternal hypertension.
迟发性产后子痫前期（PET）定义为产后 48 小时至 6 周新诊断的子痫前期。这种疾病不常见，与产前 PET 相比，并发症发生率更高。似乎需要进一步描述这种疾病。本研究旨在探讨与健康对照组相比，迟发性产后子痫前期患者的母亲心率差异。
回顾 2014-2020 年期间因迟发性产后子痫前期再次入院的所有女性的病历。将产妇生理特征数据与同期无并发症妊娠的健康对照组进行比较。
共纳入 45 例产后 6.3±2.86 天诊断为迟发性子痫前期的患者。与对照组（n=49）相比，迟发性产后患者年龄较大，分别为 34.6±5.4 岁和 32.3±4.7 岁，P=0.003。两组产妇的孕次、产次、BMI（kg/m）或分娩日血红蛋白水平无差异。与对照组相比，迟发性产后子痫前期患者的平均脉搏率较低，分别为 58±15bpm 和 83±11.6bpm，P<0.0001。迟发性发病组中只有 17%的女性脉搏率高于 70bpm，而对照组中这一比例为 83%。
迟发性产后子痫前期患者的母亲心率低是一种重要的临床特征，可能反映了母体高血压对压力感受器的反应。
