Department of General Surgery, Faculty of Medicine, Gastrointestinal Surgical Center GISC, Mansoura University, Gehan Street, Al Dakahlia Governorate, 35511, Mansoura, Egypt.
World J Surg Oncol. 2023 Mar 9;21(1):85. doi: 10.1186/s12957-023-02968-0.
Gastrointestinal stromal tumor (GIST) is a rare small intestinal tumor. Most patients usually report long-period complaints due to difficult diagnoses. A high grade of suspicion is required for early diagnosis and initiation of the proper management.
A retrospective study of all patients with small intestinal GIST who were operated in the period between January 2008 and May 2021 at Mansoura University Gastrointestinal Surgical Center (GIST).
Thirty-four patients were included in the study with a mean age of 58.15 years (± 12.65) with a male to female ratio of 1.3:1. The mean duration between onset of symptoms and diagnosis was 4.62 years (± 2.34). Diagnosis of a small intestinal lesion was accomplished through abdominal computed tomography (CT) in 19 patients (55.9%). The mean size of the tumor was 8.76 cm (± 7.76) ranging from 1.5 to 35 cm. The lesion was of ileal origin in 20 cases (58.8%) and jejunal in 14 cases (41.2%). During the scheduled follow-up period, tumor recurrence occurred in one patient (2.9%). No mortality was encountered.
Diagnosis of a small bowel GISTs requires a high grade of suspicion. Implementing new diagnostic techniques like angiography, capsule endoscopy, and enteroscopy should be encouraged when suspecting these lesions. Surgical resection is always associated with an excellent postoperative recovery profile and very low recurrence rates.
胃肠道间质瘤（GIST）是一种罕见的小肠肿瘤。由于诊断困难，大多数患者通常会出现长期的不适症状。对于早期诊断和及时采取适当的治疗措施，需要高度警惕。
回顾性分析 2008 年 1 月至 2021 年 5 月在曼苏拉大学胃肠外科中心接受手术治疗的小肠 GIST 患者的所有资料。
研究共纳入 34 例患者，平均年龄为 58.15 岁（±12.65），男女比例为 1.3:1。症状出现至诊断的平均时间为 4.62 年（±2.34）。19 例（55.9%）患者通过腹部计算机断层扫描（CT）诊断出小肠病变，14 例（41.2%）患者通过胶囊内镜诊断出小肠病变。肿瘤平均大小为 8.76cm（±7.76），范围为 1.5 至 35cm。病变起源于回肠 20 例（58.8%），空肠 14 例（41.2%）。在计划的随访期间，1 例患者（2.9%）肿瘤复发。无死亡病例。
诊断小肠 GIST 需要高度警惕。怀疑存在这些病变时，应鼓励采用新的诊断技术，如血管造影、胶囊内镜和小肠镜检查。手术切除始终与良好的术后恢复情况和非常低的复发率相关。
