Galvin G M, Jelinek G A
Department of Emergency Medicine, Fremantle Hospital, Western Australia.
Arch Emerg Med. 1987 Sep;4(3):169-72. doi: 10.1136/emj.4.3.169.
Midazolam meleate, a water soluble 1,4 benzodiazepine, was used intravenously in 20 patients suffering seizures, of whom 12 were in status epilepticus. In all cases, midazolam in a dose of 2.5-15 mg rapidly terminated the seizure. There were no complications from the use of midazolam. The causes of the seizures were varied but alcohol-withdrawal seizures were the single largest cause. Thirteen patients were taking some form of anticonvulsant medication but only three were in the therapeutic range. Midazolam is seen to be an effective agent in the emergency treatment of seizures.
美索比妥咪达唑仑是一种水溶性的1,4 - 苯二氮䓬类药物，对20例癫痫患者进行了静脉注射，其中12例为癫痫持续状态。在所有病例中，2.5 - 15毫克剂量的咪达唑仑迅速终止了癫痫发作。使用咪达唑仑没有出现并发症。癫痫发作的原因多种多样，但酒精戒断性癫痫是最主要的单一原因。13例患者正在服用某种形式的抗惊厥药物，但只有3例处于治疗范围内。咪达唑仑被视为癫痫紧急治疗中的一种有效药物。
