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大麻所致肺损伤:一例报告及文献综述

Marijuana-Induced Lung Injury: A Case Report and a Review of the Literature.

作者信息

Phan Alexander T, Hu Janie, Ghantarchyan Henrik H, Nguyen Viet-Tien P, Hasan Mufadda

机构信息

Internal Medicine, Arrowhead Regional Medical Center, Colton, USA.

Pulmonary and Critical Care Medicine, Arrowhead Regional Medical Center, Colton, USA.

出版信息

Cureus. 2023 Feb 4;15(2):e34635. doi: 10.7759/cureus.34635. eCollection 2023 Feb.

DOI:10.7759/cureus.34635
PMID:36895540
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9989321/
Abstract

Marijuana is a commonly abused illicit substance around the world, and lung injury related to its use has seldom been cited in the literature. Most cases describe marijuana-induced lung injury via vaping and the use of butane hash oil; however, no cases, to our knowledge, have associated lung injury related to marijuana smoke in the form of rolled "blunts" or cigarettes. We describe the case of a patient who presented to the hospital due to chest computed tomography findings demonstrating diffuse bilateral opacifications without signs of systemic inflammatory response syndrome. Bronchoscopy with bronchoalveolar lavage and sputum cultures failed to identify an infectious etiology, and serologies were negative for autoimmune etiologies. We aim to contribute to the limited body of literature describing marijuana-induced lung injury.

摘要

大麻是一种在全球被普遍滥用的非法物质,而与使用大麻相关的肺损伤在文献中很少被提及。大多数病例描述的是通过吸电子烟和使用丁烷大麻油导致的大麻诱发的肺损伤;然而,据我们所知,尚无病例将与大麻烟雾相关的肺损伤与卷制的“钝器”或香烟形式联系起来。我们描述了一名患者的病例,该患者因胸部计算机断层扫描结果显示双侧弥漫性混浊且无全身炎症反应综合征迹象而入院。支气管镜检查及支气管肺泡灌洗和痰培养未能确定感染病因,血清学检查排除自身免疫病因。我们旨在为描述大麻诱发肺损伤的有限文献做出贡献。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7214/9989321/571d8340fcba/cureus-0015-00000034635-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7214/9989321/d04e27e00eb3/cureus-0015-00000034635-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7214/9989321/571d8340fcba/cureus-0015-00000034635-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7214/9989321/d04e27e00eb3/cureus-0015-00000034635-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7214/9989321/571d8340fcba/cureus-0015-00000034635-i02.jpg

相似文献

1
Marijuana-Induced Lung Injury: A Case Report and a Review of the Literature.大麻所致肺损伤:一例报告及文献综述
Cureus. 2023 Feb 4;15(2):e34635. doi: 10.7759/cureus.34635. eCollection 2023 Feb.
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本文引用的文献

1
A presentation of E-Cigarette vaping associated lung injury (EVALI) caused by THC-Containing electronic smoking device.由含四氢大麻酚的电子烟装置引起的电子烟相关肺损伤(EVALI)病例报告。
Respir Med Case Rep. 2020 Jul 10;31:101154. doi: 10.1016/j.rmcr.2020.101154. eCollection 2020.
2
Cannabis Butane Hash Oil Dabbing Induced Lung Injury Mimicking Atypical Pneumonia.大麻丁烷哈希油吸食导致类似非典型肺炎的肺损伤
Cureus. 2020 Feb 18;12(2):e7033. doi: 10.7759/cureus.7033.
3
Analysis of bronchoalveolar lavage samples collected from 30 patients with drug-induced pneumonitis.
对30例药物性肺炎患者采集的支气管肺泡灌洗样本进行分析。
Respir Investig. 2020 May;58(3):204-211. doi: 10.1016/j.resinv.2020.01.002. Epub 2020 Feb 26.
4
"Tree-in-Bloom": Severe Acute Lung Injury Induced by Vaping Cannabis Oil.“开花中的树”:吸食大麻油引发的严重急性肺损伤
Ann Am Thorac Soc. 2017 Mar;14(3):468-470. doi: 10.1513/AnnalsATS.201612-974LE.
5
Severe Pneumonitis after Inhalation of Butane Hash Oil.吸入丁烷大麻油后发生的重症肺炎
Ann Am Thorac Soc. 2016 Jun;13(6):991-2. doi: 10.1513/AnnalsATS.201602-101LE.
6
Consensus statement for the diagnosis and treatment of drug-induced lung injuries.药物性肺损伤诊断与治疗的共识声明。
Respir Investig. 2013 Dec;51(4):260-77. doi: 10.1016/j.resinv.2013.09.001. Epub 2013 Oct 28.
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Drug-induced pneumonitis: thin-section CT findings in 60 patients.药物性肺炎:60例患者的薄层CT表现
Radiology. 2002 Sep;224(3):852-60. doi: 10.1148/radiol.2243011236.