Zhang Elissa Jie, Toh James Wei Tatt
Department of Surgery, Westmead Hospital, Sydney, 2145 NSW, Australia.
The University of Sydney, Westmead Clinical School, Sydney, 2145 NSW, Australia.
J Surg Case Rep. 2023 Mar 7;2023(3):rjad105. doi: 10.1093/jscr/rjad105. eCollection 2023 Mar.
Stercoral perforation is a rare but life-threatening condition that is increasingly being recognised as a sequelae of severe constipation. We present the case of a 45-year-old female who presented with stercoral perforation secondary to severe constipation related to adjuvant chemotherapy for colorectal cancer on a background of long-term antipsychotic medications. Chemotherapy-induced neutropaenia posed an additional treatment consideration in the management of sepsis associated with stercoral perforation. This case demonstrated that the morbidity and mortality from constipation especially in at risk patients cannot be underestimated.
粪性穿孔是一种罕见但危及生命的疾病，越来越被认为是严重便秘的后遗症。我们报告一例45岁女性患者，她因长期服用抗精神病药物，在接受结直肠癌辅助化疗后出现严重便秘，继发粪性穿孔。化疗引起的中性粒细胞减少在与粪性穿孔相关的脓毒症管理中是另一个需要考虑的治疗因素。该病例表明，便秘的发病率和死亡率，尤其是在高危患者中，不可低估。
