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病例报告:腹腔内侵袭性纤维瘤病:妊娠剧吐的罕见病因。

Case report: Intra-abdominal aggressive fibromatosis: A rare cause of hyperemesis.

作者信息

Zou Zilin, Ye Guannan, Xu Saiqun, Liu Wei, Wang Weining

机构信息

The Affiliated Changsha Hospital, Hengyang Medical School, University of South China, Changsha, China.

Department of Gastroenterology, The First Hospital of Changsha, Changsha, China.

出版信息

Front Surg. 2023 Feb 21;10:1108225. doi: 10.3389/fsurg.2023.1108225. eCollection 2023.

DOI:10.3389/fsurg.2023.1108225
PMID:36896261
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9989300/
Abstract

RATIONALE

Aggressive fibromatosis is a rare and locally infiltrative monoclonal fibroblastic proliferation with lack of metastatic potential. We describe a rare case of intra-abdominal aggressive fibromatosis on young female with hyperemesis.

PATIENT CONCERNS

A 23-year-old female was admitted with hyperemesis and loss of weight.

DIAGNOSES

According to imaging findings and immunohistology findings, a diagnosis of intra-abdominal aggressive fibromatosis was formulated.

OUTCOMES

After the surgery, no evidence of local recurrence was noted during the 6 months of follow-up.

LESSONS

AF may explain why pregnant women may have severe hyperemesis.

摘要

原理

侵袭性纤维瘤病是一种罕见的、局部浸润性的单克隆成纤维细胞增殖性疾病,无转移潜能。我们描述了一例年轻女性患有妊娠剧吐的腹腔内侵袭性纤维瘤病罕见病例。

患者情况

一名23岁女性因妊娠剧吐和体重减轻入院。

诊断

根据影像学和免疫组织学检查结果,确诊为腹腔内侵袭性纤维瘤病。

结果

手术后,在6个月的随访中未发现局部复发迹象。

经验教训

侵袭性纤维瘤病可能解释了为什么孕妇会出现严重的妊娠剧吐。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d7f/9989300/0b8b33e194c4/fsurg-10-1108225-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d7f/9989300/1da09fb5ec00/fsurg-10-1108225-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d7f/9989300/00eb6e2d7cc6/fsurg-10-1108225-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d7f/9989300/0b8b33e194c4/fsurg-10-1108225-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d7f/9989300/1da09fb5ec00/fsurg-10-1108225-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d7f/9989300/00eb6e2d7cc6/fsurg-10-1108225-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d7f/9989300/0b8b33e194c4/fsurg-10-1108225-g003.jpg

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Cancer Treat Res Commun. 2022;31:100562. doi: 10.1016/j.ctarc.2022.100562. Epub 2022 Apr 16.
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Sporadic desmoid fibromatosis of the neck after dorsal spondylodesis of the cervical spine.
颈椎后路融合术后颈部散发性硬纤维瘤病
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Cancer Rep (Hoboken). 2021 Dec;4(6):e1411. doi: 10.1002/cnr2.1411. Epub 2021 Jun 24.
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Clinicopathological features of 70 desmoid-type fibromatoses confirmed by β-catenin immunohistochemical staining and CTNNB1 mutation analysis.β-连环蛋白免疫组织化学染色和 CTNNB1 基因突变分析证实的 70 例韧带样纤维瘤病的临床病理特征。
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World J Clin Oncol. 2019 Apr 24;10(4):183-191. doi: 10.5306/wjco.v10.i4.183.
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