Kasinathan Kasirajan, Marimuthu Karunakaran, Samayanan Selvam, Yim Jin-Heong
Division of Advanced Materials Engineering, Kongju National University, Budaedong 275, Seobuk-gu, Cheonan-si, Chungnam 31080, South Korea.
Thin Film and Nano Science Research Lab, Department of Physics, Alagappa Government Arts College, Karaikudi, 630 003, India.
J Mater Chem B. 2023 Apr 5;11(14):3089-3096. doi: 10.1039/d2tb02451a.
Organic dyes and microorganisms in industrial wastewater have harmed both the environment and human health. In this present study, the biological and photocatalytic properties of a synthesized biogenic chitosan functionalized WS@TiO hybrid nanocomposite (NC) are investigated. The chitosan-functionalized WS@TiO hybrid nanocomposite (NC) was synthesized hydrothermally. Its microstructure and compositional properties were studied. The antibacterial activity against , and (Gram-positive) and , and (Gram-negative) was evaluated. The NC exhibits the highest antibacterial activity against at bacterial inhibition zones of 27 mm. It also showed remarkable anticancer effects in MCF-7 cells (cell inhibition of 74% at 100 μg mL). The biocompatibility of the composite was tested against the Vero (kidney epithelial) cell line. The results suggest that the NC had no obvious cytotoxicity. Also, the NC showed good photocatalytic performance (degradation rate of 89.43% at 150 min; = 0.0175 min). The results suggest that chitosan functionalized WS@TiO NCs are a potential candidate for biological and environmental applications.
工业废水中的有机染料和微生物对环境和人类健康都造成了危害。在本研究中,对合成的生物源壳聚糖功能化WS@TiO杂化纳米复合材料(NC)的生物学和光催化性能进行了研究。壳聚糖功能化WS@TiO杂化纳米复合材料(NC)通过水热法合成。研究了其微观结构和组成特性。评估了对金黄色葡萄球菌、枯草芽孢杆菌(革兰氏阳性菌)以及大肠杆菌、铜绿假单胞菌(革兰氏阴性菌)的抗菌活性。NC对金黄色葡萄球菌表现出最高的抗菌活性,抑菌圈为27毫米。它在MCF - 7细胞中也显示出显著的抗癌效果(在100μg/mL时细胞抑制率为74%)。针对Vero(肾上皮)细胞系测试了该复合材料的生物相容性。结果表明NC没有明显的细胞毒性。此外,NC表现出良好的光催化性能(150分钟时降解率为89.43%;k = 0.0175分钟)。结果表明壳聚糖功能化WS@TiO NCs是生物和环境应用的潜在候选材料。