Department of Traditional Chinese Medicine, Chang Gung Memorial Hospital, Chiayi, Taiwan.
School of Traditional Chinese Medicine, Chang Gung University, Taoyuan, Taiwan.
J Womens Health (Larchmt). 2023 May;32(5):616-622. doi: 10.1089/jwh.2022.0303. Epub 2023 Mar 10.
Mastitis is a common disorder among postpartum women. The discomfort and pain caused by mastitis may lead to the discontinuation of breastfeeding. Large-scale epidemiological studies examining mastitis are limited. Accordingly, the present study used a nationwide population-based database to collect information about all postpartum women in Taiwan to determine the incidence of and related factors for mastitis. This retrospective population-based study used the National Health Insurance Research Database to collect records of patients with mastitis during 2008-2017 and then linked the collected data to the Taiwan Birth Registry. We included women diagnosed as having lactational mastitis within 6 months of delivery. A multivariable logistic regression model was used to compare the risk of mastitis between parity in multiparous women. We identified 1,686,167 deliveries in 1,204,544 women. 19,794 women with 20,163 deliveries had a medical claim for mastitis. The incidence proportion of mastitis for 6 months postpartum was ∼1.19% and highest during the first month after delivery. Multivariable logistic regression revealed that multiparous women with a history of mastitis were likely to experience mastitis again after subsequent deliveries (adjusted odds ratio = 5.86; 95% confidence interval = 5.21-6.58). The Kaplan-Meier curve indicated that primiparous women had a higher risk of mastitis than did multiparous women (log-rank test, < 0.001). Mastitis generally occurred during the first month postpartum, and primiparous women had a higher risk of mastitis than did multiparous women. Furthermore, multiparous women with a history of mastitis had a 5.86-fold increased risk of recurrence during subsequent deliveries.
乳腺炎是产后妇女的常见疾病。乳腺炎引起的不适和疼痛可能导致母乳喂养的中断。大规模的流行病学研究对乳腺炎的研究有限。因此，本研究使用全国性的基于人群的数据库收集了台湾所有产后妇女的信息，以确定乳腺炎的发病率和相关因素。
这项回顾性基于人群的研究使用了国家健康保险研究数据库，收集了 2008 年至 2017 年乳腺炎患者的记录，并将收集到的数据与台湾出生登记处进行了关联。我们纳入了在分娩后 6 个月内被诊断为哺乳期乳腺炎的妇女。多变量逻辑回归模型用于比较多产妇中不同胎次的乳腺炎风险。
我们确定了 1204544 名妇女的 1686167 次分娩。19794 名妇女的 20163 次分娩有乳腺炎的医疗索赔。产后 6 个月乳腺炎的发病率约为 1.19%，分娩后第一个月最高。多变量逻辑回归显示，有乳腺炎病史的多产妇在随后的分娩中再次发生乳腺炎的可能性更大（调整后的优势比=5.86；95%置信区间=5.21-6.58）。Kaplan-Meier 曲线表明，初产妇发生乳腺炎的风险高于多产妇（对数秩检验，<0.001）。乳腺炎通常发生在产后第一个月，初产妇发生乳腺炎的风险高于多产妇。此外，有乳腺炎病史的多产妇在随后的分娩中复发的风险增加了 5.86 倍。
