Mitochondrial pyruvate carrier--a possible link between gluconeogenesis and ketogenesis in the liver.
作者信息
Kümmel L
机构信息
Laboratory for Endocrinology & Metabolism, Charles University, Faculty of Medicine, Prague, Czechoslovakia.
出版信息
Biosci Rep. 1987 Jul;7(7):593-7. doi: 10.1007/BF01119777.
PMID:3689883
Abstract
Effects of various ketogenic substrates on gluconeogenesis from lactate or alanine were compared. The results suggest that, in intact liver cells, cytoplasmic pyruvate is transported into mitochondria in exchange for intramitochondrially generated acetoacetate. An interrelationship between gluconeogenesis and ketogenesis may thus exist in the liver at the level of mitochondrial pyruvate carrier.
摘要
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