Spevak S E, Dmitrieva O F, Vinogradov V A, Dmitriev A D, Kizim E A
Biull Eksp Biol Med. 1987 Dec;104(12):730-3.
Naloxone partially inhibited skin wound contraction and completely blocked acceleration of wound healing in rats with stimulated lacrimal glands. Endorphins were detected in lacrimal glands. Alteration of functional activity of the lacrimal glands produces a considerable effect on pain sensitivity and endorphin blood concentration. Opioid peptides have a considerable effect on the functioning of the lacrimal apparatus and are involved in injury-induced reactions, regulating pain sensitivity, structural homeostasis and producing an anti-stress effect.
纳洛酮可部分抑制刺激泪腺的大鼠的皮肤伤口收缩，并完全阻断伤口愈合加速。在泪腺中检测到内啡肽。泪腺功能活动的改变对疼痛敏感性和内啡肽血浓度有相当大的影响。阿片肽对泪器功能有相当大的影响，并参与损伤诱导反应，调节疼痛敏感性、结构稳态并产生抗应激作用。
