Il'inskiĭ O B, Spevak S E, Kochetkov N V, Solov'eva A I, Krasnikova T L
Biull Eksp Biol Med. 1985 Jul;100(7):91-3.
A hypothesis is advanced that nociceptive stimulation activates the functional system of wound healing. Experiments were made to investigate whether the lacrimal glands, which are activated due to pain, are involved in the system of healing. Rat experiments have demonstrated that nociceptive stimulation of the lacrimal glands accelerates the repair of cutaneous wounds by 26 to 30%. Lacrimectomy accompanied by distension of wound rims (up to 26% by the 3d-4th hour) inhibits the rate of healing by 18 to 20%. Intraperitoneal injection of a lacrimal gland extract activates healing in lacrimectomized rats. The data obtained suggest that the lacrimal glands are involved in wound healing.
一种假说被提出,即伤害性刺激会激活伤口愈合的功能系统。开展了实验以研究因疼痛而被激活的泪腺是否参与愈合系统。大鼠实验表明,对泪腺进行伤害性刺激可使皮肤伤口的修复加速26%至30%。泪腺切除并伴有伤口边缘扩张(到第3至4小时扩张达26%)会使愈合速度减慢18%至20%。腹腔注射泪腺提取物可激活泪腺切除大鼠的愈合过程。所获得的数据表明泪腺参与伤口愈合。