Constenla Maria, Palenzuela Oswaldo
Departament de Biologia Animal, de Biologia Vegetal i Ecologia and Servei de Diagnostic Patologic en Peixos, Universitat Autonoma de Barcelona (UAB), 08193 Barcelona, Spain.
Instituto de Acuicultura Torre de la Sal (IATS, CSIC), 12595 Ribera de Cabanes, Spain.
Animals (Basel). 2023 Mar 5;13(5):935. doi: 10.3390/ani13050935.
is a genus of intestinal amoebae which stands among the least known human protists. Previous studies on amoebic systemic granulomatosis of a marine fish () resulted in the unexpected characterization of a new organism which was related to and named . The existence of multiple reports of systemic granulomatosis caused presumptively by unidentified amoebae in goldfish lead us to investigate the organism involved in goldfish disease. Analysed goldfish presented small whitish nodules in the kidney, which correspond to chronic granulomatous inflammatory reactions with a ring-layer of amoebae in the periphery. Amoebae were amitochondriate and were located in a parasitophorous vacuole within macrophages, as previous studies on this condition in goldfish and other freshwater fish pointed out. SSU rDNA characterization confirmed a new lineage which appears closely related to , but the molecular evidence, distinct pathological features and lack of ecological overlapping between the hosts support their assignment to a new species, . The results support the existence of a considerable unexplored diversity of spp. among fish, and their proper characterization can contribute to an understanding of Archamoebae evolution and pathogenic potential.
是肠道阿米巴的一个属，是人类已知最少的原生生物之一。先前对一种海水鱼的阿米巴系统性肉芽肿病的研究意外地鉴定出一种与相关的新生物，并将其命名为。金鱼中由不明阿米巴引起的系统性肉芽肿病的多份报告促使我们对涉及金鱼疾病的生物进行调查。分析的金鱼肾脏中出现了微小的白色结节，这对应于慢性肉芽肿性炎症反应，外周有一层阿米巴环。正如先前对金鱼和其他淡水鱼这种情况的研究所指出的，阿米巴无线粒体，位于巨噬细胞内的寄生泡中。小亚基核糖体DNA特征证实了一个与密切相关的新谱系，但分子证据、不同的病理特征以及宿主之间缺乏生态重叠支持将它们归为一个新物种，。结果支持鱼类中存在大量未被探索的物种多样性，对它们的正确鉴定有助于理解原始阿米巴的进化和致病潜力。
