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对良性前列腺增生中炎症细胞因子免疫相关相互作用的新见解

A Novel Insight into the Immune-Related Interaction of Inflammatory Cytokines in Benign Prostatic Hyperplasia.

作者信息

Naiyila Xiaokaiti, Li Jinze, Huang Yin, Chen Bo, Zhu Mengli, Li Jin, Chen Zeyu, Yang Lu, Ai Jianzhong, Wei Qiang, Liu Liangren, Cao Dehong

机构信息

Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu 610041, China.

West China School of Medicine, Sichuan University, Chengdu 610041, China.

出版信息

J Clin Med. 2023 Feb 24;12(5):1821. doi: 10.3390/jcm12051821.

Abstract

Benign prostatic hyperplasia (BPH) is a common male condition that impacts many men's quality of life by generating lower urinary tract symptoms (LUTS). In recent years, inflammation has become very common in the prostate, and BPH with inflammation has a higher International Prostate Symptom Score (IPSS) score and an enlarged prostate. Chronic inflammation leads to tissue damage and the release of pro-inflammatory cytokines, which play an important role in the pathogenesis of BPH. We will focus on current advancements in pro-inflammatory cytokines in BPH, as well as the future of pro-inflammatory cytokine research.

摘要

良性前列腺增生(BPH)是一种常见的男性疾病,通过产生下尿路症状(LUTS)影响许多男性的生活质量。近年来,炎症在前列腺中变得非常普遍,伴有炎症的BPH具有更高的国际前列腺症状评分(IPSS)和前列腺肿大。慢性炎症导致组织损伤和促炎细胞因子的释放,这些因子在BPH的发病机制中起重要作用。我们将关注BPH中促炎细胞因子的当前进展以及促炎细胞因子研究的未来。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cf0/10003138/0354fb5dfc19/jcm-12-01821-g001.jpg

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