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左心房肿瘤患者手术切除后的性别相关结果及满意度

Gender-Related Outcomes after Surgical Resection and Level of Satisfaction in Patients with Left Atrial Tumors.

作者信息

Sido Viyan, Volkwein Annika, Hartrumpf Martin, Braun Christian, Kühnel Ralf-Uwe, Ostovar Roya, Schröter Filip, Chopsonidou Sofia, Albes Johannes Maximilian

机构信息

Department of Cardiovascular Surgery, Heart Center Brandenburg, University Hospital Brandenburg Medical School, Faculty of Health Sciences Brandenburg, 16321 Bernau bei Berlin, Germany.

出版信息

J Clin Med. 2023 Mar 6;12(5):2075. doi: 10.3390/jcm12052075.

Abstract

BACKGROUND

Cardiac tumors are rare, with a low incidence of between 0.0017 and 0.19%. The majority of cardiac tumors are benign and predominantly occur in females. The aim of our study was to examine how outcomes differ between men and women.

METHODS

From 2015 to 2022, 80 patients diagnosed with suspected myxoma were operated on. In all patients, preoperative, perioperative, and postoperative data were recorded. Such patients were identified and included in a retrospective analysis focused on gender-related differences.

RESULTS

Patients were predominantly female ( = 64; 80%). The mean age was 62.76 ± 13.42 years in female patients and 59.65 ± 15.84 years in male patients ( = 0.438). The body mass index (BMI) was comparable in both groups: between 27.36 ± 6.16 in male and 27.09 ± 5.75 ( = 0.945) in female patients. Logistic EuroSCORE (LogES) (female: 5.89 ± 4.6; male: 3.95 ± 3.06; = 0.017) and EuroSCORE II (ES II) (female: 2.07 ± 2.1; male: 0.94 ± 0.45; = 0.043), both scores to predict the mortality in cardiac surgery, were significantly higher in female patients. Two patients died early, within 30 days after surgery: one male and one female patient. Late mortality was defined as the 5-year survival rate, which was 94.8%, and 15-year survival rate, which was 85.3% in our cohort. Causes of death were not related to the primary tumor operation. The follow up showed that satisfaction with surgery and long-term outcome was high.

CONCLUSION

Predominately female patients presented with left atrial tumors over a 17-year period. Relevant gender differences aside from that were not evident. Surgery could be performed with excellent early (within 30 days after surgery) and late results (follow up after discharge).

摘要

背景

心脏肿瘤较为罕见,发病率在0.0017%至0.19%之间。大多数心脏肿瘤是良性的,且主要发生在女性身上。我们研究的目的是探讨男性和女性的治疗结果有何不同。

方法

2015年至2022年期间,对80例被诊断为疑似黏液瘤的患者进行了手术。记录了所有患者术前、围手术期和术后的数据。对这些患者进行了识别,并纳入了一项关注性别差异的回顾性分析。

结果

患者以女性为主(n = 64;80%)。女性患者的平均年龄为62.76±13.42岁,男性患者为59.65±15.84岁(P = 0.438)。两组的体重指数(BMI)相当:男性患者为27.36±6.16,女性患者为27.09±5.75(P = 0.945)。预测心脏手术死亡率的逻辑欧洲心脏手术风险评估系统(Logistic EuroSCORE,LogES)(女性:5.89±4.6;男性:3.95±3.06;P = 0.017)和欧洲心脏手术风险评估系统II(EuroSCORE II,ES II)(女性:2.07±2.1;男性:0.94±0.45;P = 0.043)在女性患者中均显著更高。两名患者在术后30天内早期死亡:一名男性患者和一名女性患者。晚期死亡率定义为5年生存率,在我们的队列中为94.8%,15年生存率为85.3%。死亡原因与原发性肿瘤手术无关。随访显示,患者对手术和长期结果的满意度较高。

结论

在17年的时间里,主要是女性患者出现左心房肿瘤。除此之外,没有明显的相关性别差异。手术可以取得优异的早期(术后30天内)和晚期结果(出院后随访)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72f8/10003994/4df50d1d9907/jcm-12-02075-g001.jpg

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