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抗凝门诊的作用需要重新评估,以纳入对使用直接口服抗凝剂患者的随访。

The role of anticoagulation clinics needs to be reassessed to include follow up of patients on direct oral anticoagulants.

作者信息

Tripodi Armando, Chantarangkul Veena, Poli Daniela, Testa Sophie, Bucciarelli Paolo, Peyvandi Flora

机构信息

IRCCS Ca' Granda Maggiore Hospital Foundation, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milano, Italy.

IRCCS Ca' Granda Maggiore Hospital Foundation, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milano, Italy.

出版信息

Thromb Res. 2023 May;225:11-15. doi: 10.1016/j.thromres.2023.01.030. Epub 2023 Feb 2.

Abstract

A survey was carried out to assess the state of organization of care (including clinical and laboratory) delivered to patients on vitamin K antagonists (VKA) or direct oral anticoagulants (DOAC) followed by clinics affiliated with the Italian Federation of Thrombosis Centers (FCSA), traditionally engaged to assist anticoagulated outpatients within the country. Participants were asked to answer questions concerning (i) proportion of patients on VKA-vs-DOAC and (ii) whether dedicated testing for DOAC is available. The proportion of patients on VKA-vs-DOAC was 60 % vs 40 %. This proportion is in sharp contrast with the real-life distribution where DOAC outweigh VKA prescriptions. Furthermore, the proportion of anticoagulation clinics that provide DOAC testing (even in special situations) is relatively small (i.e., 31 % of the respondents). Furthermore, 25 % of those that declared to follow DOAC patients do not provide any testing at all. The answers to the above questions cause concerns as (i) most patients on DOAC within the country are probably on self-management, or they are managed by general practitioners or specialists outside thrombosis centers. (ii) Most patients on DOAC have no access to testing even in special situations where it would be needed. We feel that there is a (false) perception that the care needed for DOAC treatment can be much less than that required for VKA, as DOAC require prescription and not regular follow-up. A call for action should be urgently made to reassess the role of anticoagulation clinics, which should pay the same attention to patients on DOAC as those on VKA.

摘要

意大利血栓形成中心联合会(FCSA)下属的诊所,传统上致力于协助该国接受抗凝治疗的门诊患者,针对这些诊所为服用维生素K拮抗剂(VKA)或直接口服抗凝剂(DOAC)的患者提供的护理组织状况(包括临床和实验室方面)开展了一项调查。参与者被要求回答有关以下方面的问题:(i)服用VKA与DOAC的患者比例;(ii)是否有针对DOAC的专门检测。服用VKA与DOAC的患者比例为60%对40%。这一比例与现实生活中的分布情况形成鲜明对比,在现实中DOAC的处方量超过VKA。此外,提供DOAC检测(即使在特殊情况下)的抗凝门诊比例相对较小(即31%的受访者)。此外,在宣称跟踪DOAC患者的机构中,有25%根本不提供任何检测。上述问题的答案令人担忧,原因如下:(i)该国大多数服用DOAC的患者可能处于自我管理状态,或者由血栓形成中心以外的全科医生或专科医生管理。(ii)大多数服用DOAC的患者即使在需要检测的特殊情况下也无法进行检测。我们认为存在一种(错误的)观念,即DOAC治疗所需的护理可能比VKA少得多,因为DOAC需要处方且不需要定期随访。应紧急呼吁采取行动,重新评估抗凝门诊的作用,抗凝门诊应像对待服用VKA的患者一样,给予服用DOAC的患者同等关注。

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