Wen Baohong, Zhang Zanxia, Fu Kun, Zhu Jing, Liu Liang, Gao Eryuan, Qi Jinbo, Zhang Yong, Cheng Jingliang, Qu Feifei, Zhu Jinxia
Department of MRI, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Department of Oral and Maxillofacial Surgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Eur J Radiol. 2023 May;162:110748. doi: 10.1016/j.ejrad.2023.110748. Epub 2023 Feb 23.
This study aimed to explore the value of pre-/post-contrast-enhanced T1 mapping and readout segmentation of long variable echo-train diffusion-weighted imaging (RESOLVE-DWI) for the differential diagnosis of parotid gland tumors.
A total of 128 patients with histopathologically confirmed parotid gland tumors [86 benign tumors (BTs) and 42 malignant tumors (MTs)] were retrospectively recruited. BTs were further divided into pleomorphic adenomas (PAs, n = 57) and Warthin's tumors (WTs, n = 15). MRI examinations were performed before and after contrast injection to measure the longitudinal relaxation time (T1) value (T1p and T1e, respectively) and the apparent diffusion coefficient (ADC) value of the parotid gland tumors. The reduction in T1 (T1d) values and the percentage of T1 reduction (T1d%) were calculated.
The T1d and ADC values of the BTs were considerably higher than those of the MTs (all P <.05). The area under the curve (AUC) of the T1d and ADC values for differentiating between BTs and MTs of the parotid was 0.618 and 0.804, respectively (all P <.05). The AUC of the T1p, T1d, T1d%, and ADC values for differentiating between PAs and WTs was 0.926, 0.945, 0.925, and 0.996, respectively (all P >.05). The ADC and T1d% + ADC values performed better in differentiating between PAs and MTs than the T1p, T1d, and T1d% (AUC values: 0.902, 0.909, 0.660, 0.726, and 0.736, respectively). The T1p, T1d, T1d%, and T1d% + T1p values all had high diagnosis efficacy in differentiating WTs from MTs (AUC values: 0.865, 0.890, 0.852, and 0.897, respectively, all P >.05).
T1 mapping and RESOLVE-DWI can be used to differentiate parotid gland tumors quantitatively and can be complementary to each other.
本研究旨在探讨对比增强前后T1 mapping及长可变回波链扩散加权成像（RESOLVE-DWI）读出分割技术在腮腺肿瘤鉴别诊断中的价值。
回顾性纳入128例经组织病理学证实的腮腺肿瘤患者[86例良性肿瘤（BTs）和42例恶性肿瘤（MTs）]。BTs进一步分为多形性腺瘤（PAs，n = 57）和沃辛瘤（WTs，n = 15）。在注射对比剂前后进行MRI检查，测量腮腺肿瘤的纵向弛豫时间（T1）值（分别为T1p和T1e）及表观扩散系数（ADC）值。计算T1降低值（T1d）及T1降低百分比（T1d%）。
BTs的T1d和ADC值显著高于MTs（均P <.05）。T1d和ADC值鉴别腮腺BTs与MTs的曲线下面积（AUC）分别为0.618和0.804（均P <.05）。T1p,T1d,T1d%及ADC值鉴别PAs与WTs的AUC分别为0.926、0.945、0.925和0.996（均P >.05）。在鉴别PAs与MTs方面，ADC及T1d% + ADC值比T1p、T1d和TId%表现更好（AUC值分别为0.902、0.909、0.660、0.726和0.736）。T1p、T1d、T1d%及T1d% + T1p值在鉴别WTs与MTs方面均具有较高的诊断效能（AUC值分别为0.865、0.890、0.852和0.897，均P >.05）。
T1 mapping及RESOLVE-DWI可用于定量鉴别腮腺肿瘤，且二者具有互补性。
