Institute of Traditional Chinese Veterinary Medicine, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, PR China; MOE Joint International Research Laboratory of Animal Health and Food Safety, Nanjing Agricultural University, Nanjing 210095, PR China; College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, PR China.
College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, PR China.
Ecotoxicol Environ Saf. 2023 Apr 1;254:114731. doi: 10.1016/j.ecoenv.2023.114731. Epub 2023 Mar 10.
Microbes play a crucial role in maintaining health by aiding in digestion, regulating the immune system, producing essential vitamins, and preventing the colonization of harmful bacteria. The stability of the microbiota is, therefore, necessary for overall well-being. However, several environmental factors can negatively affect the microbiota, including exposure to industrial waste, i.e., chemicals, heavy metals, and other pollutants. Over the past few decades, industries have grown significantly, but the wastewater from those industries has seriously harmed the environment and the health of living beings both locally and globally. The current study investigated the effects of salt-contaminated water exposure on gut microbiota in chickens. According to our findings, amplicon sequencing showed 453 OTUs across control and salt-contaminated water exposure groups. Proteobacteria, Firmicutes, and Actinobacteriota were the most dominant phyla in the chickens regardless of treatment. However, exposure to salt-contaminated water resulted in a remarkable decline in gut microbial diversity. While, the beta diversity revealed substantial differences in major gut microbiota components. Moroever, microbial taxonomic investigation indicated that the proportions of one bacterial phylum and nineteen bacterial genera significantly decreased. Also, the levels of one bacterial phylum and thirty three bacterial genera markedly increased under salt-contaminated water exposure, which indicates a disruption in gut microbial homeostasis. Hence the current study provides a basis to explore the effects of salt-contaminated water exposure on the health of vertebrate species.
微生物在维持健康方面发挥着至关重要的作用，它们有助于消化、调节免疫系统、产生必需的维生素，并防止有害细菌的定植。因此，微生物群的稳定性对于整体健康是必要的。然而，一些环境因素会对微生物群产生负面影响，包括接触工业废物，例如化学品、重金属和其他污染物。在过去的几十年中，工业得到了显著发展，但这些工业产生的废水已经严重损害了环境和全球生物的健康。本研究调查了含盐废水暴露对鸡肠道微生物群的影响。根据我们的发现，扩增子测序显示在对照组和含盐废水暴露组中都有 453 个 OTUs。无论处理方式如何，变形菌门、厚壁菌门和放线菌门都是鸡肠道中最占优势的门。然而，含盐废水暴露导致肠道微生物多样性显著下降。而β多样性揭示了主要肠道微生物群组成部分的显著差异。此外，微生物分类学研究表明，一个细菌门和十九个细菌属的比例显著下降。此外，在含盐废水暴露下，一个细菌门和三十三个细菌属的水平明显增加，这表明肠道微生物群的稳态被破坏。因此，本研究为探索含盐废水暴露对脊椎动物健康的影响提供了基础。
