Etlik City Hospital, Department of Cardiology,Ankara, Turkey.
Pursaklar State Hospital, Department of Cardiology, Ankara, Turkey.
J Electrocardiol. 2023 Jul-Aug;79:8-12. doi: 10.1016/j.jelectrocard.2023.02.003. Epub 2023 Feb 24.
The pathological effects of acute pulmonary embolism (APE) on the right ventricle are one of the most important determinants of mortality in patients with APE. Frontal QRS-T angle (fQRSTa) predicts ventricular pathology and poor prognosis in many different cardiovascular diseases. In this study, we investigated whether there is a significant relationship between fQRSTa and APE severity.
A total of 309 patients were included in this retrospective study. The severity of APE was classified as massive (high risk), submassive (intermediate risk), or nonmassive (low risk). fQRSTa calculated from standard ECGs.
fQRSTa was significantly higher in massive APE patients (p < 0.001). fQRSTa was also found to be significantly higher in the in-hospital mortality group (p < 0.001). fQRSTa was an independent risk factor for the development of massive APE (odds ratio:1.033; 95% CI: 1.012-1.052; p < 0.001).
Our study showed that increased fQRSTa predicts high-risk APE patients and mortality in APE patients.
急性肺栓塞(APE)对右心室的病理影响是APE 患者死亡率的最重要决定因素之一。额面 QRS-T 夹角(fQRSTa)可预测多种不同心血管疾病中的心室病理和预后不良。在本研究中,我们研究了 fQRSTa 与 APE 严重程度之间是否存在显著关系。
本回顾性研究共纳入 309 例患者。APE 的严重程度分为大块(高风险)、次大块(中风险)或非大块(低风险)。从标准心电图计算 fQRSTa。
大块 APE 患者的 fQRSTa 明显更高(p<0.001)。住院期间死亡率较高的患者 fQRSTa 也明显升高(p<0.001)。fQRSTa 是发展为大块 APE 的独立危险因素(优势比:1.033;95%可信区间:1.012-1.052;p<0.001)。
本研究表明,fQRSTa 增加可预测高危 APE 患者和 APE 患者的死亡率。