Department of Translational Medicine, Division of Urological Research, Lund University, Lund, Sweden.
Division of Oncology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden.
Eur Urol Focus. 2023 Jul;9(4):582-583. doi: 10.1016/j.euf.2023.03.001. Epub 2023 Mar 9.
Studies to date on biomarkers predictive of response to bacillus Calmette-Guérin (BCG) treatment for non-muscle-invasive bladder cancer have only identified markers with prognostic potential. There is an urgent need for larger study cohorts and for control arms comprising BCG-untreated patients to identify biomarkers with true ability to predict BCG response in classifying this patient population.
迄今为止,针对预测卡介苗(BCG)治疗非肌肉浸润性膀胱癌反应的生物标志物的研究仅鉴定出具有预后潜力的标志物。迫切需要更大的研究队列和包含未接受 BCG 治疗的患者的对照组,以鉴定真正能够预测 BCG 反应的生物标志物,从而对该患者人群进行分类。