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[鳃裂囊肿的恶性转化]

[Malignant transformation of a branchial cleft cyst].

作者信息

Jakab-Péter Kinga, Háromi István, Kaszás Bálint, Oláh Zsanett, Szanyi István, Somogyvári Krisztina

机构信息

1 Pécsi Tudományegyetem, Általános Orvostudományi Kar, Klinikai Központ, Fül-Orr-Gégészeti és Fej-Nyaksebészeti Klinika Pécs, Munkácsy M. u. 2., 7621 Magyarország.

2 Pécsi Tudományegyetem, Általános Orvostudományi Kar, Pathologiai Intézet Pécs Magyarország.

出版信息

Orv Hetil. 2023 Mar 12;164(10):388-392. doi: 10.1556/650.2023.32741.

DOI:10.1556/650.2023.32741
PMID:36906865
Abstract

Branchial cleft cyst is the most common birth defect involving the neck. Malignant transformation is known, however, differentiating from a neck metastasis of a squamous cell carcinoma of unknown primary is challenging. Even though there are strict criterias, the diagnosis of this entity remains controversial. We present the case of a 69-year-old woman, who presented with a swelling under the left side of the mandible. After diagnostic workup, fine-needle aspiration biopsy raised the suspicion of a cystic squamous cell carcinoma metastasis, therefore we performed panendoscopy and modified radical neck dissection. The pathological examination confirmed branchial cleft cyst carcinoma. After surgery, the patient received adjuvant radiation and chemotherapy. During the case workup, we present the difficulties of the diagnostic process, differential diagnostic problems, and the review of the international literature. In the case of a solitary, cystic mass on the neck without a primary tumor, we should consider the possibility of a branchiogenic carcinoma. Orv Hetil. 2023; 164(10): 388-392.

摘要

鳃裂囊肿是最常见的涉及颈部的先天性缺陷。虽然已知存在恶性转化,但将其与原发灶不明的鳞状细胞癌颈部转移瘤区分开来具有挑战性。尽管有严格的标准,但该实体的诊断仍存在争议。我们报告了一例69岁女性病例,她表现为下颌骨左侧下方肿胀。经过诊断性检查,细针穿刺活检引发了囊性鳞状细胞癌转移的怀疑,因此我们进行了全腔镜检查和改良根治性颈清扫术。病理检查证实为鳃裂囊肿癌。手术后,患者接受了辅助放疗和化疗。在病例检查过程中,我们阐述了诊断过程中的困难、鉴别诊断问题以及对国际文献的回顾。对于颈部出现孤立性囊性肿块且无原发肿瘤的情况,我们应考虑鳃源性癌的可能性。《匈牙利医学周报》。2023年;164(10):388 - 392。

相似文献

1
[Malignant transformation of a branchial cleft cyst].[鳃裂囊肿的恶性转化]
Orv Hetil. 2023 Mar 12;164(10):388-392. doi: 10.1556/650.2023.32741.
2
Metastatic squamous cell carcinoma of the gingiva appearing as a solitary branchial cyst carcinoma: diagnostic role of PET/CT.表现为孤立性鳃裂囊肿癌的牙龈转移性鳞状细胞癌:PET/CT的诊断作用
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[Inflammatory or malignant? Lessons from a cystic lateral neck lesion with a sudden onset].[炎症性还是恶性?一例突发的囊性侧颈部病变的经验教训]
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Ear Nose Throat J. 2014 Sep;93(9):E4-6. doi: 10.1177/014556131409300901.
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Squamous cell carcinoma arising in branchiogenic cyst: branchial cleft carcinoma.起源于鳃裂囊肿的鳞状细胞癌:鳃裂癌。
J Surg Oncol. 1982 Aug;20(4):201-4. doi: 10.1002/jso.2930200402.
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Branchial cleft cyst and branchial cleft cyst carcinoma, or cystic lymph node and cystic nodal metastasis?鳃裂囊肿和鳃裂囊腺癌,还是囊性淋巴结和囊性淋巴结转移?
J Laryngol Otol. 2023 Jan;137(1):31-36. doi: 10.1017/S0022215122001293. Epub 2022 Jun 17.
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Branchiogenic carcinoma with rapid growth and skin involvement: a case report.具有快速生长和皮肤累及的分支型腺癌:病例报告。
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Primary branchiogenic carcinoma: malignant degeneration of a branchial cyst, a case report.原发性鳃源性癌:鳃裂囊肿的恶性转化,一例报告。
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Squamous carcinoma arising in a branchial cleft cyst: have you ever treated one? Will you?鳃裂囊肿中发生的鳞状细胞癌:你治疗过这种病例吗?你会治疗吗?
J Laryngol Otol. 2008 Jun;122(6):547-50. doi: 10.1017/S0022215107001004. Epub 2007 Nov 16.
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Fine needle aspiration cytology versus frozen section in branchial cleft cysts.鳃裂囊肿的细针穿刺抽吸细胞学检查与冰冻切片检查对比
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引用本文的文献

1
An unanticipated case report of squamous cell carcinoma arising from a submandibular branchial cleft cyst.一例源自下颌下鳃裂囊肿的鳞状细胞癌意外病例报告。
Ann Med Surg (Lond). 2025 Apr 22;87(6):3911-3914. doi: 10.1097/MS9.0000000000003307. eCollection 2025 Jun.
2
Suppurative thyroiditis, a sign of branchiogenic fistula? Lesson based on a case report.化脓性甲状腺炎,鳃裂瘘管的一种表现?基于一例病例报告的经验教训
Radiol Case Rep. 2024 May 7;19(8):3038-3041. doi: 10.1016/j.radcr.2024.03.076. eCollection 2024 Aug.