Kahramanmaras Sutcu Imam University, School of Medicine, Department of Ophthalmology, Kahramanmaras, Turkey.
Gaziantep Islam Science and Technology University, Medical Faculty, Department of Pediatric Gastroenterology, Dr. Ersin Arslan Training and Research Hosptial, Clinics of Pediatric Gastroenterology, Gaziantep, Turkey.
Photodiagnosis Photodyn Ther. 2023 Jun;42:103502. doi: 10.1016/j.pdpdt.2023.103502. Epub 2023 Mar 11.
This study aims to measure choroidal thickness, retinal nerve fiber layer thickness, GCC thickness, and foveal thickness by optical coherence tomography and to investigate whether there is a difference between celiac patients who adhere to the gluten-free diet and who do not.
A total of 68 eyes of 34 pediatric patients diagnosed with celiac disease were included in the study. Celiac patients were divided into two groups those who adhere to the gluten-free diet and those who do not. Fourteen patients who adhere to the gluten-free diet and 20 patients who do not adhere to the gluten-free diet were included in the study. Choroidal thickness, GCC, RNFL, and foveal thickness of all subjects were measured and recorded using an optical coherence tomography device.
The mean choroidal thickness of the dieting and non-diet groups was 249.05 ± 25.60 and 244.18 ± 33.50 µm, respectively. The mean GCC thickness of the dieting and non-diet groups was 96.56 ± 6.26 and 93.83 ± 5.62 µm, respectively. The mean RNFL thickness of the dieting and non-diet groups was 108.83 ± 9.97 and 103.20 ± 9.74 µm, respectively. The mean foveal thickness of the dieting and non-diet groups was 259.25 ± 33.60 and 261.92 ± 32.94 µm, respectively. There was not a statistically significant difference between the dieting group and the non-diet group in terms of choroidal, GCC, RNFL and foveal thicknesses (p = 0.635, p = 0.207, p = 0.117, p = 0.820, respectively).
In conclusion, the present study states that adhering to a gluten-free diet does not make any difference in choroidal, GCC, RNFL, and foveal thicknesses in pediatric celiac patients.
本研究旨在通过光学相干断层扫描测量脉络膜厚度、视网膜神经纤维层厚度、GCC 厚度和黄斑中心凹厚度，并探讨坚持无麸质饮食和不坚持无麸质饮食的乳糜泻患者之间是否存在差异。
本研究共纳入 34 例经诊断为乳糜泻的儿科患者的 68 只眼。将乳糜泻患者分为两组，一组坚持无麸质饮食，另一组不坚持无麸质饮食。研究纳入了 14 名坚持无麸质饮食的患者和 20 名不坚持无麸质饮食的患者。使用光学相干断层扫描仪测量并记录所有受试者的脉络膜厚度、GCC、RNFL 和黄斑中心凹厚度。
饮食组和非饮食组的平均脉络膜厚度分别为 249.05 ± 25.60 µm 和 244.18 ± 33.50 µm。饮食组和非饮食组的平均 GCC 厚度分别为 96.56 ± 6.26 µm 和 93.83 ± 5.62 µm。饮食组和非饮食组的平均 RNFL 厚度分别为 108.83 ± 9.97 µm 和 103.20 ± 9.74 µm。饮食组和非饮食组的平均黄斑中心凹厚度分别为 259.25 ± 33.60 µm 和 261.92 ± 32.94 µm。在脉络膜、GCC、RNFL 和黄斑中心凹厚度方面，饮食组与非饮食组之间无统计学差异（p = 0.635、p = 0.207、p = 0.117、p = 0.820）。
综上所述，本研究表明，在儿科乳糜泻患者中，坚持无麸质饮食并不会对脉络膜、GCC、RNFL 和黄斑中心凹厚度产生影响。
