Department of Pharmacy, Zhongshan Hospital, Fudan University, Shanghai, 200032, People's Republic of China.
Department of Respiratory Medicine, Zhongshan Hospital, Fudan University, Shanghai, 200032, People's Republic of China.
BMC Psychol. 2023 Mar 12;11(1):68. doi: 10.1186/s40359-023-01097-3.
To investigated the influence of illness perceptions and other risk factors related to poor asthma control and quality of life in adult outpatients with asthma in China.
Patients with a confirmed asthma diagnosis were recruited from the outpatient clinic at Zhongshan Hospital, Fudan University in Shanghai. Sociodemographic, psychological, and asthma related variables were assessed in all participants. Patients' illness perceptions, medication adherence, asthma control, and quality of life were assessed using validated questionnaires, such as the Brief Illness Perception Questionnaire, Medication Adherence Rating Scale (MARS-A), the Asthma Control Test, and the Mini Asthma Quality of Life Questionnaire. Multiple linear regressions and logistic regressions were used to examine the associations between illness perceptions, medication adherence behaviors, and disease outcome (i.e., asthma control and quality of life).
A total of two hundred thirty-one (231) outpatients with asthma were included in this cross-sectional study, 80 of whom (34.6%) had asthma that was uncontrolled. Patients who perceived their life (β = - 0.197, p < 0.001) and emotions (β = - 0.294, p < 0.001) as severely affected by the illness were more likely to have a lower quality of life, findings that were statistically significant. Also, patients who believed they had a higher degree of personal control over their illness (β = 0.333, p < 0.001), and had better medication adherence (β = 0.250, p < 0.001) were found to have a better quality of life.
Our study indicated that illness perceptions and medication adherence have a significant impact on disease outcome. Both of these factors should be considered when determining the best health care practices or constructing a predictive intervention model for patients with uncontrolled asthma.
调查疾病认知和其他与中国成人门诊哮喘患者哮喘控制不良和生活质量相关的风险因素对哮喘的影响。
本研究招募了来自上海复旦大学中山医院门诊的确诊哮喘患者。所有参与者均评估了社会人口统计学、心理学和哮喘相关变量。使用经过验证的问卷评估患者的疾病认知、药物依从性、哮喘控制和生活质量，例如简短疾病认知问卷、药物依从性评定量表（MARS-A）、哮喘控制测试和迷你哮喘生活质量问卷。多元线性回归和逻辑回归用于检查疾病认知、药物依从行为与疾病结局（即哮喘控制和生活质量）之间的关系。
本横断面研究共纳入 231 例门诊哮喘患者，其中 80 例（34.6%）哮喘未得到控制。认为疾病严重影响生活（β=-0.197，p<0.001）和情绪（β=-0.294，p<0.001）的患者生活质量较低，具有统计学意义。此外，认为自己对疾病有更高程度的个人控制（β=0.333，p<0.001）和更好的药物依从性（β=0.250，p<0.001）的患者生活质量更好。
我们的研究表明，疾病认知和药物依从性对疾病结局有显著影响。在确定最佳医疗保健实践或构建未控制哮喘患者的预测干预模型时，应考虑这两个因素。
