Children's Hospital Los Angeles, Los Angeles (all authors); Department of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles (Sayegh, Sherer).
Am J Psychother. 2023 Sep 1;76(3):93-99. doi: 10.1176/appi.psychotherapy.20210042. Epub 2023 Mar 13.
Interpersonal psychotherapy (IPT) is an evidence-based treatment for depression, demonstrating efficacy with adolescents and young adults. Social support is proposed to be an important treatment component and may be helpful for adolescents and young adults with chronic illness. The authors sought to assess the feasibility of delivering IPT to this population and to examine changes in depressive symptoms and perceived social support.
An open-label feasibility trial of group-based IPT was conducted for adolescents and young adults with chronic illness (N=17). The 12-session group IPT was concurrent with group members' individual psychotherapy, and group IPT was focused on providing support in navigating interpersonal challenges related to the participants' chronic illness. Participants completed questionnaires assessing depressive symptoms and social support before treatment, midtreatment (6 weeks), and after treatment (12 weeks). Generalized estimating equation models, adjusted for repeated measures, were used to assess changes in depressive symptoms and social support over the course of treatment.
Deidentified clinical examples illustrated how IPT was practiced in a community mental health setting. Evidence for the feasibility of group IPT was mixed. Although participants had poor session attendance, there was a significant decrease in depressive symptoms (β=-2.94, 95% CI=-5.30 to -0.59, p=0.014) and a significant increase in perceived social support (β=4.24, 95% CI=0.51 to 7.98, p=0.026) by the end of treatment.
IPT may help address depressive symptoms and enhance social support among adolescents and young adults with chronic illness. Further research and adaptation are needed to address feasibility challenges in delivering group IPT to this population.
人际心理治疗（IPT）是一种针对抑郁症的循证治疗方法，已被证明对青少年和年轻人有效。社会支持被认为是治疗的一个重要组成部分，可能对患有慢性疾病的青少年和年轻人有帮助。作者试图评估将 IPT 用于该人群的可行性，并研究抑郁症状和感知社会支持的变化。
对患有慢性疾病的青少年和年轻人（N=17）进行了基于小组的 IPT 开放性可行性试验。12 节小组 IPT 与小组成员的个体心理治疗同时进行，小组 IPT 侧重于提供与参与者慢性疾病相关的人际挑战方面的支持。参与者在治疗前、治疗 6 周时和治疗 12 周时完成了评估抑郁症状和社会支持的问卷。使用广义估计方程模型，根据重复测量进行调整，评估治疗过程中抑郁症状和社会支持的变化。
匿名临床示例说明了 IPT 如何在社区心理健康环境中实施。小组 IPT 可行性的证据喜忧参半。尽管参与者的课程出席率较低，但抑郁症状显著下降（β=-2.94，95%CI=-5.30 至-0.59，p=0.014），感知社会支持显著增加（β=4.24，95%CI=0.51 至 7.98，p=0.026），治疗结束时。
IPT 可能有助于解决患有慢性疾病的青少年和年轻人的抑郁症状，并增强他们的社会支持。需要进一步的研究和改编，以解决向该人群提供小组 IPT 的可行性挑战。
