血流导向装置治疗未破裂椎动脉夹层动脉瘤：单中心经验
Flow diverters in the treatment of unruptured vertebral artery dissecting aneurysm: A single-center experience.
作者信息
Lu Xiaoyang, Zhang Yuansheng, Zhou Hu, Jian Lipeng, Yin Shi, Li Tao, Huang Wei
机构信息
Department of Neurosurgery, The First People's Hospital of Yunnan Province, The Affiliated Hospital of Kunming University of Science and Technology, Kunming, Yunnan, China.
The Affiliated Hospital of Kunming University of Science and Technology, Kunming, Yunnan, China.
出版信息
Front Neurol. 2023 Feb 22;14:1050619. doi: 10.3389/fneur.2023.1050619. eCollection 2023.
OBJECTIVE
To evaluate the efficacy and safety of flow diverters (FD) in the treatment of vertebral artery dissecting aneurysm (VADA).
METHODS
A total of 16 patients with 17 unruptured VADAs treated with FD from January 2017 to May 2021 were included. Data of clinical outcomes and radiographic examination were collected and assessed by the modified Rankin Scale (mRS) and O'Kelly-Marotta (OKM) grading scale.
RESULTS
All patients were treated with a single FD. No perioperative complications occurred. The mean age was 55.1 years old. The mean size of the aneurysm was 10.4 mm. All patients had a favorable occlusion (OKM D + C3) result and the complete occlusion rate in the 6th month was 66.7% (OKM D). The mean clinical follow-up time was 7.8 months, and all patients had a good clinical outcome (mRS = 0). No procedure-related complication occurred at the last follow-up time.
CONCLUSION
FD is an effective and safe tool for treating unruptured VADA. Long-term prospective studies with a large sample are still needed to confirm these findings in the future.
目的
评估血流导向装置（FD）治疗椎动脉夹层动脉瘤（VADA）的疗效和安全性。
方法
纳入2017年1月至2021年5月期间16例接受FD治疗的17个未破裂VADA患者。收集临床结局和影像学检查数据，并采用改良Rankin量表（mRS）和奥凯利 - 马罗塔（OKM）分级量表进行评估。
结果
所有患者均接受单一FD治疗。未发生围手术期并发症。平均年龄为55.1岁。动脉瘤平均大小为10.4mm。所有患者均获得良好的闭塞（OKM D + C3）结果，6个月时的完全闭塞率为66.7%（OKM D）。平均临床随访时间为7.8个月，所有患者临床结局良好（mRS = 0）。末次随访时未发生与手术相关的并发症。
结论
FD是治疗未破裂VADA的有效且安全的工具。未来仍需要大样本的长期前瞻性研究来证实这些发现。
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