Sain Baijaeek, Blake Megan, Goyal Kanchan, Kaur Harsimran, Robinson Kristina
St. Mary's Hospital, Imperial College Healthcare NHS Trust London, London, UK.
General Surgery, The Grange University Hospital, Aneurin Bevan University Health Board, NHS, Cwmbran, Wales, UK.
J Surg Case Rep. 2023 Mar 9;2023(3):rjad111. doi: 10.1093/jscr/rjad111. eCollection 2023 Mar.
Primary non-Hodgkin's lymphoma (NHL) of the urinary bladder is a rare event, with diffuse large B-cell lymphoma (DLBCL) being the most common form of NHL and urinary bladder lymphoma. It is an aggressive tumour with a poor prognosis if not recognised and treated early. The diagnosis is supported by radiological imaging and confirmed by histology, which shows the characteristic morphology of this lesion with further immunohistochemical analysis. Here we present a case of Epstein-Barr virus-positive DLBCL confirmed by an immunohistochemistry panel, along with a brief review of the literature focusing on diagnosis, treatment and outcome of this rare tumour.
原发性膀胱非霍奇金淋巴瘤(NHL)是一种罕见疾病,弥漫性大B细胞淋巴瘤(DLBCL)是NHL及膀胱淋巴瘤最常见的形式。它是一种侵袭性肿瘤,若不及早识别和治疗,预后较差。放射影像学检查有助于诊断,组织学检查可确诊,其显示了该病变的特征性形态,并需进一步进行免疫组化分析。在此,我们报告一例经免疫组化检测确诊的爱泼斯坦-巴尔病毒阳性DLBCL病例,并简要回顾文献,重点关注这种罕见肿瘤的诊断、治疗及预后。