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膀胱原发性弥漫性大B细胞淋巴瘤

Primary diffuse large B-cell lymphoma of the bladder.

作者信息

Hayashi Akinori, Miyakawa Yoshitaka, Bokuda Kota, Kimura Toshinori, Nakashima Emiko, Irie Rie, Sugiura Hitoshi, Suzuki Takahiro, Ohsone Yasuo, Akizuki Satoshi

机构信息

Department of Internal Medicine, Kawasaki Municipal Hospital.

出版信息

Intern Med. 2009;48(16):1403-6. doi: 10.2169/internalmedicine.48.2110. Epub 2009 Aug 17.

Abstract

Primary lymphoma of the bladder is quite rare; primarily, it is extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT-lymphoma). There is only one case report of primary diffuse large B-cell lymphoma (DLBCL) of the bladder, accompanied by diffuse wall thickening of the bladder. Here, we report a second case of primary DLBCL of the bladder in a 75-year-old woman patient, whose initial presentation was acute renal failure. Three courses of R-CHOP chemotherapy were effective to treat acute renal failure caused by post-renal obstruction and to attain clinical remission.

摘要

膀胱原发性淋巴瘤相当罕见;主要是黏膜相关淋巴组织的结外边缘区B细胞淋巴瘤(MALT淋巴瘤)。仅有一例膀胱原发性弥漫性大B细胞淋巴瘤(DLBCL)的病例报告,伴有膀胱壁弥漫性增厚。在此,我们报告第二例膀胱原发性DLBCL,患者为一名75岁女性,最初表现为急性肾衰竭。三个疗程的R-CHOP化疗有效治疗了由肾后梗阻引起的急性肾衰竭并实现临床缓解。

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