Lalwani Muskan, Taksande Avinash B
Physiology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Wardha, IND.
Cureus. 2023 Feb 7;15(2):e34751. doi: 10.7759/cureus.34751. eCollection 2023 Feb.
COVID-19-infected survivors are reporting persistent anomalies upon hospital discharge. After one year, a sizable percentage of COVID-19 survivors still have persistent symptoms affecting different bodily systems. Evidence suggests that the lungs are the most affected organs by COVID-19. It may also cause corollary and other medical issues. The literature on preceding COVID-19 infections reviews that patients may also experience chronic impairment in breathing characteristics after discharge. The outcome of COVID-19 may remain for weeks to months after the initial recovery. Our goal is to determine the superiority of the restrictive pattern, obstructive pattern, and adjusted diffusion in patients post-COVID-19 contamination and to explain the distinctive opinions of breathing characteristics used with those patients. Therefore, lung function tests were measured post-discharge for three to 12 months. According to estimates, 80% of severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2)-infected patients experienced one or more chronic symptoms. Multidisciplinary teams are required to develop preventive measures, rehabilitation methods, and scientific control plans with a completely patient-centered attitude for long-term COVID-19 care. Clarifying the pathophysiologic mechanisms, creating and testing specific interventions, and treating patients with long-term COVID-19 are urgently needed. The goal of this review is to locate research evaluating COVID-19's long-term effects. A person who has suffered from COVID-19 in the past showed changes in their pulmonary function test. So, we have to notice the changes and recovery from post-COVID-19 effects. COVID-19 survivors were observed in an eventual observational study and continuously examined three, six, and 12 months after having COVID-19 infections. We evaluated the clinical features and concentrations of circulating pulmonary epithelial and endothelial markers in COVID-19 survivors with normal or lower diffusion capacity for carbon monoxide (DLCO) six months after discharge to analyze risk factors and underlying pathophysiology.
新冠病毒感染康复者出院后报告存在持续异常情况。一年后，相当大比例的新冠病毒康复者仍有影响不同身体系统的持续症状。有证据表明，肺部是受新冠病毒影响最严重的器官。它还可能引发相关及其他医学问题。关于既往新冠病毒感染的文献综述显示，患者出院后呼吸特征也可能出现慢性损害。新冠病毒感染的影响在最初康复后可能会持续数周甚至数月。我们的目标是确定新冠病毒感染后患者限制性模式、阻塞性模式和调整后弥散的优势，并解释这些患者呼吸特征的独特观点。因此，在出院后三至十二个月进行了肺功能测试。据估计，80%的严重急性呼吸综合征冠状病毒2型（SARS-CoV-2）感染患者出现了一种或多种慢性症状。需要多学科团队以完全以患者为中心的态度制定预防措施、康复方法和科学控制计划，以进行长期的新冠病毒感染护理。迫切需要阐明病理生理机制、制定并测试具体干预措施以及治疗长期新冠病毒感染患者。本综述的目的是查找评估新冠病毒长期影响的研究。一名曾感染新冠病毒的患者肺功能测试出现了变化。所以，我们必须注意新冠病毒感染后影响的变化和恢复情况。在一项最终观察性研究中对新冠病毒康复者进行了观察，并在感染新冠病毒后三个月、六个月和十二个月进行持续检查。我们评估了出院六个月后一氧化碳弥散能力（DLCO）正常或较低的新冠病毒康复者的临床特征以及循环肺上皮和内皮标志物的浓度，以分析危险因素和潜在病理生理学。
