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颈哑铃型神经鞘瘤瘤内出血导致的急性神经功能恶化:1例罕见病例报告及文献复习

Acute Neurological Aggravation Caused by Intratumoral Hemorrhage of a Cervical Dumbbell Schwannoma: Report of a Rare Case and Literature Review.

作者信息

Sakashita Kotaro, Koda Masao, Takahashi Hiroshi, Funayama Toru, Yamazaki Masashi

机构信息

Department of Orthopaedic Surgery, Faculty of Medicine, University of Tsukuba, Tsukuba, JPN.

出版信息

Cureus. 2023 Feb 6;15(2):e34682. doi: 10.7759/cureus.34682. eCollection 2023 Feb.

Abstract

Schwannomas are one of the most common types of primary intraspinal tumors. We report a rare case of neurological aggravation due to the intratumoral hemorrhage of a cervical schwannoma. A 65-year-old man presented with lower extremity weakness developing gradually. Tumor resection was performed one week after neurological aggravation occurred. After surgery, he recovered dramatically. There are vascular and mechanical hypotheses for the etiology of intratumoral hemorrhage of schwannoma. In the present case, falling and antiplatelet drugs may have caused the intratumoral hemorrhage. Optimal surgical timing remains controversial. Some reports reveal patients recovered well after urgent surgery. However, even if urgent surgery is performed, some have neurological sequelae. Others reveal patients recovered well after elective surgery without any sequelae. Because previous reports reveal the surgical procedure may damage the spinal cord, urgent surgery may not be compulsory and elective surgery may be a better treatment option. Further investigation is needed to clarify the etiology and optimal timing for surgical treatment of intratumoral hemorrhage.

摘要

神经鞘瘤是最常见的原发性椎管内肿瘤类型之一。我们报告一例因颈段神经鞘瘤瘤内出血导致神经功能恶化的罕见病例。一名65岁男性逐渐出现下肢无力。在神经功能恶化发生一周后进行了肿瘤切除术。术后,他恢复显著。关于神经鞘瘤瘤内出血的病因有血管和机械两种假说。在本病例中,跌倒和抗血小板药物可能导致了瘤内出血。最佳手术时机仍存在争议。一些报告显示患者在急诊手术后恢复良好。然而,即使进行了急诊手术,一些患者仍有神经后遗症。其他报告显示患者在择期手术后恢复良好且无任何后遗症。由于先前的报告显示手术过程可能损伤脊髓,急诊手术可能并非必需,择期手术可能是更好的治疗选择。需要进一步研究以阐明瘤内出血的病因及手术治疗的最佳时机。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/299e/9994380/78c2e248a284/cureus-0015-00000034682-i01.jpg

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