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黑素细胞性病变诊断与预后的新技术

New Technologies in Diagnosis and Prognosis of Melanocytic Lesions.

作者信息

Marushchak Olga, Yakubov Rebecca, Yakubov Rose, Goldenberg Gary

机构信息

Dr. Marushchak is with the Department of Internal Medicine at Mount Sinai Morningside-West in New York, New York.

Ms. Rebeeca Yakubov and Ms. Rose Yakubov are with McMaster University in Hamilton, Ontario.

出版信息

J Clin Aesthet Dermatol. 2023 Feb;16(2):44-49.

PMID:36909871
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10005807/
Abstract

Analysis of morphological characteristics for the diagnosis of melanoma remains a challenge. New technologies for the diagnosis and prognosis of melanocytic lesions have been emerging to ensure earlier and more accurate detection. In this article, we review multiple technologies that improve melanoma diagnostic accuracy such as electrical impedance spectroscopy, pigmented lesion assay, reflectance confocal microscopy, and gene expression profile tests.

摘要

分析黑色素瘤的形态学特征以进行诊断仍然是一项挑战。用于黑素细胞病变诊断和预后评估的新技术不断涌现,以确保更早、更准确地检测。在本文中,我们综述了多种提高黑色素瘤诊断准确性的技术,如电阻抗光谱、色素沉着病变检测、反射式共聚焦显微镜和基因表达谱检测。

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New Technologies in Diagnosis and Prognosis of Melanocytic Lesions.黑素细胞性病变诊断与预后的新技术
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Role of In Vivo Reflectance Confocal Microscopy in the Analysis of Melanocytic Lesions.体内反射共聚焦显微镜在黑素细胞性病变分析中的作用
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Acta Derm Venereol. 2022 Jul 26;102:adv00751. doi: 10.2340/actadv.v102.1105.
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本文引用的文献

1
Performance of Gene Expression Profile Tests for Prognosis in Patients With Localized Cutaneous Melanoma: A Systematic Review and Meta-analysis.用于局部皮肤黑色素瘤患者预后的基因表达谱检测的性能:系统评价和荟萃分析。
JAMA Dermatol. 2020 Sep 1;156(9):953-962. doi: 10.1001/jamadermatol.2020.1731.
2
Real-World Utility of a Non-Invasive Gene Expression Test to Rule Out Primary Cutaneous Melanoma: A Large US Registry Study.一项用于排除原发性皮肤黑色素瘤的非侵入性基因表达检测的真实世界效用:一项美国大型登记研究
J Drugs Dermatol. 2020 Mar 1;19(3):257-262.
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Problematic methodology in a systematic review and meta-analysis of DecisionDx-Melanoma.
J Am Acad Dermatol. 2020 Nov;83(5):e357-e358. doi: 10.1016/j.jaad.2020.04.186. Epub 2020 Jun 9.
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Molecular risk prediction in cutaneous melanoma: A meta-analysis of the 31-gene expression profile prognostic test in 1,479 patients.皮肤黑色素瘤的分子风险预测:对 1479 例患者的 31 个基因表达谱预后检测的荟萃分析。
J Am Acad Dermatol. 2020 Sep;83(3):745-753. doi: 10.1016/j.jaad.2020.03.053. Epub 2020 Mar 27.
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Reflectance confocal microscopy diagnostic accuracy for malignant melanoma in different clinical settings: systematic review and meta-analysis.不同临床环境下反射式共聚焦显微镜对恶性黑色素瘤的诊断准确性:系统评价与荟萃分析
J Eur Acad Dermatol Venereol. 2020 Oct;34(10):2268-2279. doi: 10.1111/jdv.16248. Epub 2020 Feb 27.
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Use of the Pigmented Lesion Assay to rapidly screen a patient with numerous clinically atypical pigmented lesions.使用色素沉着病变检测法对患有大量临床非典型色素沉着病变的患者进行快速筛查。
JAAD Case Rep. 2019 Nov 20;5(12):1048-1050. doi: 10.1016/j.jdcr.2019.10.004. eCollection 2019 Dec.
7
The diagnostic accuracy of dermoscopy and reflectance confocal microscopy for amelanotic/hypomelanotic melanoma: a systematic review and meta-analysis.皮肤镜检查和反射式共聚焦显微镜对无色素/色素减退性黑色素瘤的诊断准确性:一项系统评价和荟萃分析。
Br J Dermatol. 2020 Aug;183(2):210-219. doi: 10.1111/bjd.18722. Epub 2019 Dec 22.
8
Impact on clinical practice of a non-invasive gene expression melanoma rule-out test: 12-month follow-up of negative test results and utility data from a large US registry study.非侵入性基因表达黑色素瘤排除试验对临床实践的影响:来自美国一项大型注册研究的阴性试验结果及效用数据的12个月随访
Dermatol Online J. 2019 May 15;25(5):13030/qt61w6h7mn.
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Early outcome of a 31-gene expression profile test in 86 AJCC stage IB-II melanoma patients. A prospective multicentre cohort study.86 例 AJCC 分期 IB-II 期黑色素瘤患者 31 基因表达谱检测的早期结果。一项前瞻性多中心队列研究。
J Eur Acad Dermatol Venereol. 2019 May;33(5):857-862. doi: 10.1111/jdv.15454. Epub 2019 Feb 28.
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Guidance of sentinel lymph node biopsy decisions in patients with T1-T2 melanoma using gene expression profiling.使用基因表达谱对 T1-T2 期黑色素瘤患者的前哨淋巴结活检决策进行指导。
Future Oncol. 2019 Apr;15(11):1207-1217. doi: 10.2217/fon-2018-0912. Epub 2019 Jan 29.