养老院中老年人与虚弱相关的人类微生物组失调。
Frailty-associated dysbiosis of human microbiotas in older adults in nursing homes.
机构信息
Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.
UConn Center on Aging, UConn Health, Farmington, CT, USA.
出版信息
Nat Aging. 2022 Oct;2(10):876-877. doi: 10.1038/s43587-022-00289-7. Epub 2022 Oct 14.
Abstract
Our longitudinal study comparing the skin, gut and oral microbiomes of community-dwelling older adults and nursing home residents showed striking changes known to be linked to antibiotic resistance and disease risk. Such shifts were associated with frailty, not chronological age, and were most pronounced in the skin, the primary reservoir for infection risk.
摘要
我们的纵向研究比较了社区居住的老年人和养老院居民的皮肤、肠道和口腔微生物组，结果显示出与抗生素耐药性和疾病风险相关的显著变化。这些变化与虚弱有关，而不是与年龄有关，而且在皮肤中最为明显，皮肤是感染风险的主要储库。
Zotero 插件