Zhang Lingfeng, Xu Yantao, Ma Yingxu, Xie Tianjian, Liu Chan, Liu Qiming
Department of Cardiovascular Medicine, The Second Xiangya Hospital of Central South University, Changsha, China.
Xiangya School of Medicine, Central South University, Changsha, China.
Front Cardiovasc Med. 2023 Feb 22;10:1071198. doi: 10.3389/fcvm.2023.1071198. eCollection 2023.
Transient receptor potential vanilloid (TRPV) is one of the transient receptor potential protein groups; cardiovascular system disease is a crucial cause of mortality among people globally.
This article is intended to accomplish a bibliometric analysis of the trends and public interest since TRPV was reported for the first time.
The article summarized the Web of Science (WOS) Core Collection on the relationship between TRPV and cardiovascular system disease each year from 2000 to 2021. Data extraction and visualization were completed by R package bibliometrix. Keyword citation burst and co-citation networks were generated and produced by CiteSpace. The map evaluating the distribution of country and region was painted in GunnMap 2 (lert.co.nz). The ranking was performed using the Standard Competition Ranking method. Co-authorship and co-occurrence were analyzed with VOSviewer.
After removing duplicated data, books, conference proceedings, and articles of uncertain age, 493 were included, and 17 were excluded. The pattern of publication years showed that the number of publications increased rapidly from 2008 to 2021 with no peak in the number of publications until 2021. The geographical distribution pattern revealed a considerable gap in the number of publications between the United States, China, and other countries, with East Asian institutions leading the world in this area. The pattern of co-authorship showed that 77 institutions were divided into 19 clusters, each covering one country or region.These results suggest that intercontinental cooperation among institutions should be strengthened. The core authors section displayed the change in the most published authors. Keyword analysis listed six burst keywords. Co-citation analysis of references from 2011 to 2021 showed the number and centrality of citations to leading articles.
Our findings reveal trends and public interest in transient receptor potential vanilloid for cardiovascular disease. These findings suggest that the field has experienced significant growth since 2008, with the United States and China in dominant positions. Our findings also suggest that intercontinental cooperation should be strengthened, and that future research hotspots may focus on pharmacological mechanisms and in-depth exploration of drug clinical trials and new clinical disease application areas such as hypertension, diabetes, and cardiac arrhythmias, which could serve as a foundation for further research.
瞬时受体电位香草酸亚型（TRPV）是瞬时受体电位蛋白家族之一；心血管系统疾病是全球人群死亡的一个关键原因。
本文旨在对首次报道TRPV以来的研究趋势和公众关注度进行文献计量分析。
文章总结了2000年至2021年每年Web of Science（WOS）核心合集中TRPV与心血管系统疾病之间关系的文献。数据提取和可视化由R包bibliometrix完成。关键词共现爆发和共被引网络由CiteSpace生成。国家和地区分布地图在GunnMap 2（lert.co.nz）中绘制。排名采用标准竞争排名法。合作作者和共现分析使用VOSviewer进行。
去除重复数据、书籍、会议论文和出版年份不确定的文章后，纳入493篇，排除17篇。出版年份模式显示，2008年至2021年出版物数量迅速增加，直到2021年出版物数量才达到峰值。地理分布模式显示，美国、中国与其他国家在出版物数量上存在相当大的差距，东亚机构在该领域领先世界。合作作者模式显示，77个机构分为19个集群，每个集群覆盖一个国家或地区。这些结果表明，应加强机构间的洲际合作。核心作者部分展示了发文最多的作者的变化。关键词分析列出了六个爆发关键词。2011年至2021年参考文献的共被引分析显示了对领先文章的引用数量和中心性。
我们的研究结果揭示了瞬时受体电位香草酸亚型在心血管疾病方面的研究趋势和公众关注度。这些结果表明，自2008年以来该领域经历了显著增长，美国和中国占据主导地位。我们的研究结果还表明，应加强洲际合作，未来的研究热点可能集中在药理机制以及对高血压、糖尿病和心律失常等药物临床试验和新临床疾病应用领域的深入探索上，这可为进一步研究奠定基础。
