Mohamed Ahmed, Yao Mark, Saw Sonia, Clark Amanda, Madaan Sanjeev
Department of Urology, Dartford and Gravesham NHS Foundation Trust, Dartford, UK.
Department of Pathology, Maidstone and Tunbridge Wells NHS Foundation Trust, Maidstone, Kent, UK.
JRSM Open. 2023 Mar 7;14(3):20542704231153562. doi: 10.1177/20542704231153562. eCollection 2023 Mar.
Prostate cancer and pancreatic cancer are often complex pathologies that affect millions of patients worldwide. However, the incidence of a distant collision metastasis of both malignancies remains a rare and often poorly documented incidence.
A 75-year-old male patient with past history of prostate cancer on maximal androgen blockade was recently diagnosed with pancreatic cancer for which he underwent radical surgical resection of pancreas with curative intent. A metastatic lung nodule was noted on surveillance CT imaging and, subsequently, biopsied. A diagnosis of collision metastasis from two distinct primary malignancies was histopathologically confirmed following immunohistochemical evaluation.
We report the first case of collision metastasis of prostate and pancreatic adenocarcinomata to a lung nodule to the best of our knowledge.
前列腺癌和胰腺癌通常是复杂的病症，影响着全球数百万患者。然而，这两种恶性肿瘤发生远处碰撞转移的发生率仍然很低，且相关记录往往很少。
一名75岁男性患者，既往有前列腺癌病史，正在接受最大雄激素阻断治疗，最近被诊断出患有胰腺癌，并接受了旨在治愈的胰腺根治性手术切除。在监测CT成像中发现了一个转移性肺结节，随后进行了活检。经过免疫组化评估，病理组织学证实为来自两种不同原发性恶性肿瘤的碰撞转移。
据我们所知，我们报告了首例前列腺癌和胰腺腺癌碰撞转移至肺结节的病例。
