Otorhinolaryngology-Head and Neck Surgery, University Hospitals Leuven.
Department of Oncology, Section Head and Neck Oncology, KU Leuven, Leuven, Belgium.
Curr Opin Otolaryngol Head Neck Surg. 2023 Apr 1;31(2):146-154. doi: 10.1097/MOO.0000000000000876. Epub 2023 Feb 9.
A vagal paraganglioma is a rare head and neck tumor arising from the paraganglionic tissue within the perineurium of the vagus nerve, anywhere along the course of the nerve. Due to its proximity to the internal carotid artery, the internal jugular vein and the lower cranial nerves, this disorder poses significant diagnostic and therapeutic challenges. The diagnostic workup and management keep on evolving.
This article gives a concise update of the clinical spectrum and the current state-of-the-art diagnostic workup and management of vagal paraganglioma.
Every patient with suspected vagal paraganglioma needs to be evaluated by a multidisciplinary team. The management strategy is selected depending on the growth rate of the tumor, the age and fitness of the patient, the number of affected cranial nerves, the metabolic activity of the paraganglioma, and the eventual multicentricity. An algorithm guiding the clinician through the different treatment options is presented.
迷走神经副神经节瘤是一种罕见的头颈部肿瘤，起源于迷走神经神经外膜内的副神经节组织，可发生在神经的任何部位。由于其靠近颈内动脉、颈内静脉和颅神经下部，该疾病存在显著的诊断和治疗挑战。诊断方法和管理措施在不断发展。
本文简要介绍了迷走神经副神经节瘤的临床特征，以及目前该疾病的最新诊断方法和管理措施。
所有疑似迷走神经副神经节瘤的患者均需由多学科团队进行评估。治疗策略的选择取决于肿瘤的生长速度、患者的年龄和健康状况、受影响颅神经的数量、副神经节瘤的代谢活性以及最终的多中心性。本文提出了一个指导临床医生选择不同治疗方案的算法。
