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HIV 感染者男男性行为者的 HIV 披露与 HIV 护理连续体结局之间的关联:系统评价和荟萃分析。

Associations between HIV disclosure and HIV care continuum outcomes among men who have sex with men living with HIV: systematic review and meta-analysis.

机构信息

South Carolina SmartState Center for Healthcare Quality, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA.

Department of Health Promotion, Education and Behavior, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA.

出版信息

AIDS Care. 2023 Dec;35(12):1982-1997. doi: 10.1080/09540121.2023.2188159. Epub 2023 Mar 13.

Abstract

The objective of this study is to synthesize the existing empirical literature and perform a systematic review and meta-analysis on the relationship between HIV disclosure and engagement in the HIV care continuum among men who have sex with men living with HIV. Twenty-three studies were included, with thirteen quantitative studies and ten qualitative studies. Meta-analytic techniques were used to compute and aggregate effect sizes (odds ratio [OR] and their confidence intervals [95%CI]) for the quantitative studies and a thematic analysis was employed for qualitative studies. Given the small number of eligible studies, meta-analysis was only conducted for the linkage to care outcome, where a positive association was observed from the pooled estimation (OR = 1.51, 95%CI [1.15, 1.99]). Regarding ART initiation, retention in care, and viral suppression outcomes, most of the individual studies revealed a positive association between HIV disclosure and these outcomes. Thematic analysis from qualitative studies complemented the quantitative findings by incorporating the approaching and avoidance motivations underlying the relationship between non-HIV disclosure and the participation in HIV care continuum. The small number of available studies limits the definitive conclusions, and more research is needed to ascertain the magnitude of effect sizes.

摘要

本研究旨在综合现有实证文献,对男男性行为者中艾滋病毒披露与艾滋病毒护理连续体参与之间的关系进行系统回顾和荟萃分析。共纳入 23 项研究,其中包括 13 项定量研究和 10 项定性研究。采用荟萃分析技术计算和汇总定量研究的效应大小(比值比[OR]及其 95%置信区间[95%CI]),并对定性研究进行主题分析。由于合格研究的数量较少,仅对与护理关联的结果进行了荟萃分析,汇总估计显示存在正相关(OR=1.51,95%CI[1.15,1.99])。关于 ART 启动、护理保留和病毒抑制结果,大多数单独的研究表明,艾滋病毒披露与这些结果之间存在正相关。定性研究的主题分析通过纳入非艾滋病毒披露与参与艾滋病毒护理连续体之间关系的接近和回避动机,补充了定量研究结果。现有研究数量较少限制了确定结论,需要进一步研究以确定效应大小的幅度。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/496e/10497729/6218d0d9152c/nihms-1883145-f0001.jpg

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