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肯尼亚男同性恋者、双性恋者及其他男男性行为者的艾滋病护理参与情况及抗逆转录病毒治疗依从性:基于定性研究的多层次模型

HIV care engagement and ART adherence among Kenyan gay, bisexual, and other men who have sex with men: a multi-level model informed by qualitative research.

作者信息

Graham Susan M, Micheni Murugi, Secor Andrew, van der Elst Elise M, Kombo Bernadette, Operario Don, Amico K Rivet, Sanders Eduard J, Simoni Jane M

机构信息

a Departments of Medicine , University of Washington , Seattle , WA , USA.

b Departments of Global Health , University of Washington , Seattle , WA , USA.

出版信息

AIDS Care. 2018 Aug;30(sup5):S97-S105. doi: 10.1080/09540121.2018.1515471. Epub 2019 Jan 22.

Abstract

Gay, bisexual, and other men who have sex with men (GBMSM) are highly stigmatized and male-male sex is often criminalized in sub-Saharan Africa, impeding access to quality care for sexual health, HIV prevention, and treatment. To better understand HIV care engagement and antiretroviral therapy (ART) adherence among GBMSM in this context, a conceptual model incorporating sociocultural factors is needed. We conducted a qualitative study of barriers to and facilitators of HIV care engagement and ART adherence among Kenyan GBMSM, informed by a conceptual model based on an access, information, motivation, and behavioral skills (access-IMB) model, with trust in providers and stigma and discrimination as a priori factors of interest. We conducted 30 semi-structured interviews with HIV-positive Kenyan GBMSM, of whom 20 were taking ART and 10 had not yet initiated treatment. A deductive approach was used to confirm the relevance of basic concepts of the access-IMB model, while an inductive approach was used to identify content that emerged from men's lived experiences. Access-related information, motivation, and behavioral skills appeared relevant to HIV care engagement and ART adherence, with stigma and discrimination appearing consistently across discourse exploring facilitators and barriers. Trusted providers and supportive family and friends helped many men, and resilience-related concepts such as selective disclosure of GBMSM status, connection to lesbian, gay, bisexual, and transgender (LGBT) organizations, self-acceptance, goal-setting, social identity and altruism emerged as important facilitators. Findings suggest a need to increase support from providers and peers for Kenyan GBMSM living with HIV infection. In addition, they point toward the potential value of interventions that provide opportunities to build or enhance one's sense of community belonging in order to improve HIV care engagement and promote ART adherence for this vulnerable population.

摘要

男同性恋者、双性恋者以及其他与男性发生性行为的男性(GBMSM)在撒哈拉以南非洲地区遭受着严重的污名化,男男性行为在该地区常常被定为犯罪,这阻碍了他们获得性健康、艾滋病毒预防和治疗方面的优质护理。为了更好地理解在这种背景下GBMSM对艾滋病毒护理的参与情况以及抗逆转录病毒疗法(ART)的依从性,需要一个纳入社会文化因素的概念模型。我们基于一个基于获取、信息、动机和行为技能(access - IMB)模型的概念模型,对肯尼亚GBMSM在艾滋病毒护理参与和ART依从性方面的障碍及促进因素进行了定性研究,并将对医疗服务提供者的信任以及污名和歧视作为预先关注的因素。我们对30名感染艾滋病毒的肯尼亚GBMSM进行了半结构化访谈,其中20人正在接受ART治疗,10人尚未开始治疗。采用演绎法来确认access - IMB模型基本概念的相关性,同时采用归纳法来识别从男性生活经历中浮现出的内容。与获取相关的信息、动机和行为技能似乎与艾滋病毒护理参与和ART依从性相关,在探讨促进因素和障碍的讨论中,污名和歧视始终存在。值得信赖的医疗服务提供者以及支持性的家人和朋友帮助了许多男性,一些与复原力相关的概念,如选择性披露GBMSM身份、与女同性恋、男同性恋、双性恋和跨性别者(LGBT)组织的联系、自我接纳、目标设定、社会认同和利他主义,成为了重要的促进因素。研究结果表明,需要增加医疗服务提供者和同伴对感染艾滋病毒的肯尼亚GBMSM的支持。此外,研究结果还指出了一些干预措施的潜在价值,这些干预措施提供了建立或增强社区归属感的机会,以改善艾滋病毒护理参与情况并促进这一弱势群体对ART的依从性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed50/6436548/b1cd9f129d2f/CAIC_A_1515471_F0001_OC.jpg

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