Blast Induced Neurotrauma Branch, Walter Reed Army Institute of Research, Silver Spring, MD, 20910, USA.
Ann Biomed Eng. 2023 Jul;51(7):1616-1626. doi: 10.1007/s10439-023-03174-5. Epub 2023 Mar 13.
The biomechanics and efficacy of personal protective equipment in mitigating injuries from blast overpressure remain unclear. The objectives of this study were to define intrathoracic pressures in response to blast wave (BW) exposure and biomechanically evaluate a soft-armor vest (SA) at diminishing these perturbations. Male Sprague-Dawley rats were instrumented with pressure sensors in the thorax and were exposed laterally to multiple exposures ranging from 33 to 108 kPa BW with SA and without SA. There were significant increases in rise time, peak negative pressure, and negative impulse in the thoracic cavity compared to the BW. Esophageal measurements were increased to a greater extent when compared to the carotid and the BW for all parameters (except positive impulse, which decreased). SA minimally altered the pressure parameters and energy content. This study establishes the relationship of external blast flow conditions and intra-body biomechanical responses in the thoracic cavity of rodents with and without SA.
个人防护装备在减轻爆炸超压损伤方面的生物力学和效果仍不清楚。本研究的目的是确定胸部对爆炸波（BW）暴露的压力，并从生物力学角度评估软质装甲背心（SA）对这些干扰的作用。雄性 Sprague-Dawley 大鼠胸部装有压力传感器，并从侧面接受多次暴露，BW 范围从 33 到 108 kPa。与 BW 相比，胸腔内的上升时间、峰值负压和负压冲量均显著增加。与颈动脉和 BW 相比，食道测量的所有参数（除了正冲量减小）都增加了更大的幅度。SA 最小地改变了压力参数和能量含量。本研究建立了有和没有 SA 的啮齿动物胸部外爆炸流条件和体内生物力学反应之间的关系。
