Bauru School of Dentistry, University of São Paulo, Bauru, São Paulo, Brazil.
Carrera de Odontologia, Universidad Catõlica de Santiago de Guayaquil, Guayaquil, Guayas, Ecuador.
J Oral Implantol. 2023 Feb 1;49(1):102-113. doi: 10.1563/aaid-joi-D-22-00014.
The objective of this systematic review was to identify the available scientific evidence on bone substitutes (BSs) compared with autogenous bone grafts (ABGs) for regeneration of horizontal bone resorption in the anterior maxillary alveolar process, aiming at rehabilitation with endosseous implants. This review was performed according to the PRISMA guidelines (2020) and registered in the database PROSPERO (CRD: 42017070574). The databases searched were PUBMED/MEDLINE, EMBASE, SCOPUS, SCIENCE DIRECT, WEB OF SCIENCE, and CENTRAL COCHRANE, in the English language. The Australian National Health and Medical Research Council (NHMRC) and Cochrane Risk of Bias Tool were used to assess the study's quality and risk of bias. A total of 524 papers were found. After the selection process, 6 studies were selected for review. A total of 182 patients were followed for a period of 6 to 48 months. The mean age of patients was 46.46 years, and 152 implants were installed in the anterior region. Two studies achieved a reduced graft and implant failure rate, whereas the remaining 4 studies had no losses. It may be concluded that the use of ABGs and some BSs is a viable alternative for the rehabilitation with implants in individuals with anterior horizontal bone loss. However, additional randomized controlled trials are warranted due to the limited number of papers.
本系统评价的目的是确定骨替代物（BSs）与自体骨移植物（ABGs）在再生前上颌牙槽突水平骨吸收方面的可用科学证据，旨在通过骨内植入物进行修复。本综述按照 PRISMA 指南（2020 年）进行，并在 PROSPERO 数据库（CRD：42017070574）中进行了注册。检索的数据库包括 PUBMED/MEDLINE、EMBASE、SCOPUS、SCIENCE DIRECT、WEB OF SCIENCE 和 CENTRAL COCHRANE，均为英文。使用澳大利亚国家健康与医疗研究委员会（NHMRC）和 Cochrane 偏倚风险工具评估研究的质量和偏倚风险。共发现 524 篇论文。经过筛选过程，选择了 6 项研究进行综述。共随访了 182 名患者，随访时间为 6 至 48 个月。患者的平均年龄为 46.46 岁，在前牙区植入了 152 个种植体。两项研究降低了移植物和种植体失败的风险，而其余四项研究没有发生失访。可以得出结论，在有前牙水平骨丧失的患者中，使用 ABGs 和一些 BSs 是一种可行的植入物修复替代方法。然而，由于论文数量有限，需要更多的随机对照试验来验证。
