PETcoil项目：针对第二代用于PET/MRI同步成像的可穿透射频的TOF-PET脑专用插入件的两个探测器模块的PET性能评估。

The PETcoil project: PET performance evaluation of two detector modules for a second generation RF-penetrable TOF-PET brain dedicated insert for simultaneous PET/MRI.

作者信息

Dong Qian, Chang Chen-Ming, Lee Brian J, Sacco Ilaria, Sajedi Salar, Adams Zander, Fischer Peter, Levin Craig S

机构信息

Molecular Imaging Instrumentation Laboratory, Stanford University, Stanford, CA, United States of America.

Department of Computer Science, Heidelberg University, Baden-Württemberg, Germany.

出版信息

Phys Med Biol. 2023 Apr 5;68(8). doi: 10.1088/1361-6560/acc3f2.

DOI:10.1088/1361-6560/acc3f2

PMID:36913739

Abstract

. We are developing a portable, 'RF-penetrable', brain-dedicated time of flight (TOF)-PET insert (PETcoil) for simultaneous PET/MRI.. In this paper, we evaluate the PET performance of two fully assembled detector modules for this insert design outside the MR room.. The global coincidence time resolution, global 511 keV energy resolution, coincidence count rate, and detector temperature achieved over 2 h data collection were 242.2 ± 0.4 ps full width at half maximum (FWHM), 11.19% ± 0.02% FWHM, 22.0 ± 0.1 kcps, and 23.5 °C ± 0.3 °C, respectively. The intrinsic spatial resolutions in the axial and transaxial directions were 2.74 ± 0.01 mm FWHM and 2.88 ± 0.03 mm FWHM, respectively.. These results demonstrate excellent TOF capability and the performance and stability necessary for scaling up to a full ring comprising 16 detector modules.

摘要

我们正在开发一种便携式、“射频可穿透”、专用于脑部的飞行时间（TOF）正电子发射断层扫描（PET）插入件（PET线圈），用于同时进行PET/MRI检查。在本文中，我们在磁共振成像（MR）室外部评估了针对此插入件设计的两个完全组装好的探测器模块的PET性能。在超过2小时的数据采集过程中，实现的全局符合时间分辨率、全局511 keV能量分辨率、符合计数率和探测器温度分别为半高宽（FWHM）242.2±0.4皮秒、FWHM 11.19%±0.02%、22.0±0.1千计数每秒和23.5°C±0.3°C。轴向和横向的固有空间分辨率分别为FWHM 2.74±0.01毫米和FWHM 2.88±0.03毫米。这些结果证明了其出色的TOF能力以及扩大到由16个探测器模块组成的全环所需的性能和稳定性。