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[多环芳烃对鱼类组织中单加氧酶活性的诱导及其在水污染生物监测中的应用]

[Induction of the monooxygenase activity in fish tissues by polycyclic aromatic hydrocarbons and its use in the biomonitoring of water pollution].

作者信息

Kotelevtsev S V, Stepanova L I, Ponomareva L V, Buevich G V, Limarenko I M

出版信息

Eksp Onkol. 1987;9(5):46-9.

PMID:3691392
Abstract

Monooxygenase activity changes in the liver and in other tissues of certain fish species were studied after injection of methylcholanthrene and aminoanthracene to fish. Determinations of the benz(a)pyrene hydroxylase activity and activity of 7-ethoxycoumarine 0-dealkylation in the monooxygenase system were proposed as test-systems for the control of polycyclic hydrocarbon contents in natural and waste waters. The metabolic activation (Aim's test) performed by the liver microsomal fractions of different fish species was used for the analysis of sulfate cellulose industry waste waters.

摘要

在向鱼类注射甲基胆蒽和氨基蒽后,研究了某些鱼类肝脏和其他组织中的单加氧酶活性变化。提出测定单加氧酶系统中的苯并(a)芘羟化酶活性和7-乙氧基香豆素O-脱烷基活性,作为控制天然水和废水中多环烃含量的测试系统。利用不同鱼类肝脏微粒体部分进行的代谢活化(艾姆斯试验)来分析硫酸盐纤维素工业废水。

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