Department of Infectious Diseases, Renji Hospital, Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China.
Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Am J Trop Med Hyg. 2023 Mar 13;108(5):1028-1030. doi: 10.4269/ajtmh.22-0620. Print 2023 May 3.
This study aimed to investigate the differences in clinical features and routine peripheral blood testing between coronavirus disease 2019 (COVID-19) infection and influenza B infection. Patients with COVID-19 and influenza B admitted to our fever clinic from January 1, 2022 to June 30, 2022 were recruited. A total of 607 patients were included (301 with COVID-19 infection and 306 with influenza B infection). The results of a statistical analysis showed that 1) patients with COVID-19 infection were older and had a lower temperature and shorter duration from fever onset to clinic visit than patients with influenza B infection; 2) apart from fever, viral infection symptoms appeared to be more common in patients with influenza B infection than in patients with COVID-19 infection, including sore throat, cough, muscle aches, weeping, headache, fatigue, and diarrhea (P < 0.001); and 3) compared with patients with influenza B infection, patients with COVID-19 infection had higher numbers of white blood cells and neutrophils but lower numbers of red blood cells and lymphocytes (P < 0.001). In summary, several important differences were identified between COVID-19 and influenza B, which may help to guide clinicians in their initial diagnosis of these two respiratory viral infections.
本研究旨在探讨 2019 年冠状病毒病（COVID-19）感染与乙型流感感染的临床特征和常规外周血检测结果的差异。我们从 2022 年 1 月 1 日至 2022 年 6 月 30 日招募了在发热门诊就诊的 COVID-19 和乙型流感感染患者。共纳入 607 例患者（COVID-19 感染 301 例，乙型流感感染 306 例）。统计分析结果显示：1）COVID-19 感染患者年龄较大，体温较低，发热至就诊的时间较短；2）除发热外，乙型流感感染患者出现病毒感染症状的比例高于 COVID-19 感染患者，包括咽痛、咳嗽、肌肉疼痛、流涕、头痛、乏力和腹泻（P＜0.001）；3）与乙型流感感染患者相比，COVID-19 感染患者的白细胞和中性粒细胞数较高，而红细胞和淋巴细胞数较低（P＜0.001）。综上所述，COVID-19 和乙型流感之间存在一些重要差异，可能有助于指导临床医生对这两种呼吸道病毒感染进行初步诊断。
