Intensive Care Unit, Cayenne General Hospital, Cayenne, French Guiana.
Emergency Department, Cayenne General Hospital, Cayenne, French Guiana.
Am J Trop Med Hyg. 2023 Mar 13;108(5):1014-1016. doi: 10.4269/ajtmh.22-0390. Print 2023 May 3.
We describe the clinical parameters and management of nine confirmed cases of hantavirus pulmonary syndrome reported in French Guiana since 2008. All patients were admitted to Cayenne Hospital. Seven patients were men and the mean age was 48 years (range, 19-71 years). Two phases characterized the disease. The prodromal phase was characterized by fever (77.8%), myalgia (66.7%), and gastrointestinal symptoms (vomiting and diarrhea; 55.6%) starting, on average, 5 days before the illness phase, which was characterized by respiratory failure in all patients. Five patients died (55.6%) and the length of stay in the intensive care unit was 19 days (range, 11-28 days) for survivors. Detection of two back-to-back recent cases highlights the reason to screen for hantavirus infection during the nonspecific phase of the disease, in particular when concomitant pulmonary infection and digestive disorders are observed. Specific longitudinal serological surveys must also be used to identify other potential clinical forms of the disease in French Guiana.
我们描述了自 2008 年以来在法属圭亚那报告的 9 例汉坦病毒肺综合征确诊病例的临床参数和治疗方法。所有患者均入住卡宴医院。7 名患者为男性，平均年龄为 48 岁（范围 19-71 岁）。疾病有两个阶段。前驱期以发热（77.8%）、肌肉痛（66.7%）和胃肠道症状（呕吐和腹泻；55.6%）为特征，平均在疾病期前 5 天开始，所有患者均出现呼吸衰竭。5 例患者死亡（55.6%），幸存者在重症监护病房的住院时间为 19 天（范围 11-28 天）。最近连续发现两例病例突出表明，在疾病的非特异性阶段，特别是当同时出现肺部感染和消化系统疾病时，应筛查汉坦病毒感染。还必须进行特定的纵向血清学调查，以确定法属圭亚那其他潜在的疾病临床形式。
