Kocaeli University, Faculty of Dentistry, Department of Oral and Maxillofacial Surgery, Kocaeli, 41190 Turkey.
Kocaeli University, Faculty of Dentistry, Department of Oral and Maxillofacial Surgery, Kocaeli, 41190 Turkey.
J Stomatol Oral Maxillofac Surg. 2023 Sep;124(4):101434. doi: 10.1016/j.jormas.2023.101434. Epub 2023 Mar 11.
This prospective study aimed to evaluate the changes in functional outcomes and quality of life after the injection of botulinum toxin (BTX) into the masticatory muscles for the management of myogenic temporomandibular disorders (TMDs).
This study was conducted with 45 individuals who presented with clinically myogenic TMDs according to the Diagnostic Criteria for Temporomandibular Disorders. All patients received BTX injections in the temporalis and masseter muscles. The Oral Health Impact Profile-Temporomandibular Dysfunction (OHIP-TMD) questionnaire was used to evaluate the effects of treatment on quality of life. The OHIP-TMD, visual analogue scale (VAS), and maximum mouth opening (MMO) scores before and 3 months after BTX injection were evaluated.
The preoperative and postoperative assessments revealed a statistically significant reduction (p ≤ 0.001) in the average overall OHIP-TMD scores. A significant increase in the MMO scores and a significant decrease in the VAS scores were observed (p < 0.001).
The injection of BTX into the masticatory muscles is beneficial for improving the clinical and quality of life parameters in the management of myogenic TMD.
本前瞻性研究旨在评估咀嚼肌注射肉毒毒素（BTX）治疗肌源性颞下颌关节紊乱病（TMD）后功能结果和生活质量的变化。
本研究纳入了 45 名根据颞下颌关节紊乱病诊断标准临床诊断为肌源性 TMD 的患者。所有患者均接受颞肌和咬肌 BTX 注射。采用口腔健康影响简表-颞下颌关节紊乱（OHIP-TMD）问卷评估治疗对生活质量的影响。在 BTX 注射前和注射后 3 个月评估 OHIP-TMD、视觉模拟量表（VAS）和最大张口度（MMO）评分。
术前和术后评估显示，OHIP-TMD 总分平均显著降低（p≤0.001）。MMO 评分显著增加，VAS 评分显著降低（p<0.001）。
咀嚼肌注射 BTX 有利于改善肌源性 TMD 的临床和生活质量参数。
