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Sputum periostin is a biomarker of type 2 inflammation but not airway dysfunction in asthma.

作者信息

Al-Shaikhly Taha, Murphy Ryan C, Lai Ying, Frevert Charles W, Debley Jason S, Ziegler Steven F, Wong Kit, Jia Guiquan, Holweg Cecile T J, Peters Michael C, Hallstrand Teal S

机构信息

Department of Medicine, Division of Allergy and Infectious Diseases, University of Washington, Seattle, Washington, USA.

Center for Lung Biology, University of Washington, Seattle, Washington, USA.

出版信息

Respirology. 2023 May;28(5):491-494. doi: 10.1111/resp.14491. Epub 2023 Mar 13.

DOI:10.1111/resp.14491
PMID:36914406
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10257949/
Abstract
摘要

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本文引用的文献

1
Location of eosinophils in the airway wall is critical for specific features of airway hyperresponsiveness and T2 inflammation in asthma.气道壁中嗜酸性粒细胞的位置对于哮喘气道高反应性和 T2 炎症的特定特征至关重要。
Eur Respir J. 2022 Aug 4;60(2). doi: 10.1183/13993003.01865-2021. Print 2022 Aug.
2
Periostin: contributor to abnormal airway epithelial function in asthma?骨膜蛋白:哮喘中气道上皮功能异常的促成因素?
Eur Respir J. 2021 Feb 17;57(2). doi: 10.1183/13993003.01286-2020. Print 2021 Feb.
3
Relationship between sputum periostin level and inflammatory asthma phenotypes in Egyptian patients.埃及患者痰中骨膜蛋白水平与炎症性哮喘表型的关系。
J Asthma. 2021 Oct;58(10):1285-1291. doi: 10.1080/02770903.2020.1786111. Epub 2020 Jul 1.
4
Airway epithelium-shifted mast cell infiltration regulates asthmatic inflammation via IL-33 signaling.气道上皮细胞迁移的肥大细胞浸润通过 IL-33 信号调节哮喘炎症。
J Clin Invest. 2019 Nov 1;129(11):4979-4991. doi: 10.1172/JCI126402.
5
Age-related changes in serum periostin level in allergic and non-allergic children.过敏和非过敏儿童血清骨膜蛋白水平的年龄相关变化
Allergol Int. 2019 Apr;68(2):285-286. doi: 10.1016/j.alit.2018.12.006. Epub 2019 Jan 31.
6
Asthma biomarkers in the age of biologics.生物制剂时代的哮喘生物标志物。
Allergy Asthma Clin Immunol. 2017 Nov 17;13:48. doi: 10.1186/s13223-017-0219-4. eCollection 2017.
7
Reference ranges for serum periostin in a population without asthma or chronic obstructive pulmonary disease.无哮喘或慢性阻塞性肺疾病人群的血清骨膜蛋白参考范围。
Clin Exp Allergy. 2016 Oct;46(10):1303-14. doi: 10.1111/cea.12763. Epub 2016 Jun 28.
8
Serum periostin levels correlate with airway hyper-responsiveness to methacholine and mannitol in children with asthma.血清骨膜蛋白水平与哮喘患儿气道对乙酰甲胆碱和甘露醇反应性的相关性。
Allergy. 2015 Jun;70(6):674-81. doi: 10.1111/all.12599. Epub 2015 Mar 28.
9
Sputum periostin in patients with different severe asthma phenotypes.不同严重哮喘表型患者的痰液骨膜蛋白。
Allergy. 2015 May;70(5):540-6. doi: 10.1111/all.12580. Epub 2015 Feb 18.
10
Measures of gene expression in sputum cells can identify TH2-high and TH2-low subtypes of asthma.痰细胞中基因表达的测定可识别 TH2 高和 TH2 低表型哮喘。
J Allergy Clin Immunol. 2014 Feb;133(2):388-94. doi: 10.1016/j.jaci.2013.07.036. Epub 2013 Sep 24.