一种缺氧激活的光热剂可抑制多种热休克蛋白，实现低温光热治疗。
A hypoxia-activated photothermal agent inhibits multiple heat shock proteins for low-temperature photothermal therapy.
机构信息
College of Chemistry, Chemical Engineering and Materials Science, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Institute of Molecular and Nano Science, Shandong Normal University, Jinan 250014, P. R. China.
出版信息
Chem Commun (Camb). 2023 Mar 28;59(26):3898-3901. doi: 10.1039/d2cc06598c.
PMID:36917473
Abstract
A near-infrared (NIR) organic photothermal agent (PTA) to inhibit three types of heat shock proteins (HSPs) was synthesized, which could be activated under hypoxic conditions for low-temperature photothermal therapy (PTT) of cancer.
摘要
合成了一种近红外（NIR）有机光热剂（PTA），可以抑制三种热休克蛋白（HSPs），该光热剂可以在缺氧条件下被激活，用于癌症的低温光热治疗（PTT）。
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