The Ocular Immunology and Uveitis Foundation, Waltham, MA, USA.
Massachusetts Eye Research and Surgery Institution, 1440 Main St. Ste. 201, Waltham, MA, 02451, USA.
Arthritis Res Ther. 2023 Mar 14;25(1):41. doi: 10.1186/s13075-023-03021-x.
We have read the article entitled "Similarities in clinical course and outcome between juvenile idiopathic arthritis (JIA)-associated and ANA-positive idiopathic anterior uveitis: data from a population-based nationwide study in Germany" by Heiligenhaus et al. While we appreciate the work conducted by the authors, we have several comments we would like to address. First, the follow-up interval of 2 years is too short to conclude that the clinical course between two chronic pathologies is not significantly different. Second, remission status was determined by uveitis inactivity during the 2-year follow-up visit without any mention of flare frequency or length of remission, which is not a reliable measure of uveitis control. Third, ANA-positive idiopathic anterior uveitis is not a classification with a distinct clinical phenotype, and additional reports of serologic investigations would have been helpful.
我们阅读了 Heiligenhaus 等人撰写的题为“与幼年特发性关节炎相关的和抗核抗体阳性的特发性前葡萄膜炎之间的临床病程和结局相似：来自德国的一项基于人群的全国性研究的数据”的文章。虽然我们赞赏作者所做的工作，但我们有几点评论想提出。首先，2 年的随访间隔时间太短，不足以得出两种慢性疾病的临床病程没有显著差异的结论。其次，缓解状态是通过在 2 年随访期间无葡萄膜炎活动来确定的，而没有提到炎症复发的频率或缓解的持续时间，这不是衡量葡萄膜炎控制的可靠指标。第三，抗核抗体阳性的特发性前葡萄膜炎不是一种具有独特临床表型的分类，额外的血清学检查报告将是有帮助的。
