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蜱传横纹肌溶解症:一例因无形体病导致的横纹肌溶解症和急性肾损伤罕见病例。

Tick-Borne Rhabdomyolysis: A Rare Case of Rhabdomyolysis and Acute Kidney Injury Due to Anaplasmosis.

作者信息

Dogra Megha, Thakur Manish, Kumar Amrat, Thakur Garima

机构信息

Internal Medicine, Mary Imogene Bassett Hospital, Cooperstown, USA.

Internal Medicine, Cayuga Medical Center, Ithaca, USA.

出版信息

Cureus. 2023 Feb 10;15(2):e34835. doi: 10.7759/cureus.34835. eCollection 2023 Feb.

DOI:10.7759/cureus.34835
PMID:36919073
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10008484/
Abstract

Anaplasmosis is a tick-borne illness commonly seen in the northeastern states of the United States. The most common presenting signs are fever, malaise, and body aches accompanied by leukopenia, thrombocytopenia, and transaminitis. Rhabdomyolysis and acute kidney injury are rare presentations that can lead to significant morbidity.  We present the case of a patient who presented with non-specific symptoms of malaise, fatigue, and body aches and was found to have rhabdomyolysis and acute kidney injury on laboratory workup. A presumptive diagnosis of anaplasmosis was made, and the patient was started on treatment for the same. The patient recovered successfully. Our case highlights the rare presentation of anaplasmosis with rhabdomyolysis and acute kidney injury. Physician awareness is needed for early diagnosis and preventing morbidity.

摘要

无形体病是一种常见于美国东北部各州的蜱传疾病。最常见的症状是发热、不适和全身疼痛,伴有白细胞减少、血小板减少和转氨酶升高。横纹肌溶解症和急性肾损伤是罕见的表现,可导致严重的发病率。我们报告一例患者,该患者出现不适、疲劳和全身疼痛等非特异性症状,实验室检查发现有横纹肌溶解症和急性肾损伤。初步诊断为无形体病,并开始对患者进行相应治疗。患者成功康复。我们的病例突出了无形体病合并横纹肌溶解症和急性肾损伤这种罕见的表现。需要医生提高认识以实现早期诊断并预防发病。

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引用本文的文献

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Altered Mental Status on Top of Anaplasmosis-Induced Severe Rhabdomyolysis: A Rare Clinical Presentation.无形体病诱发严重横纹肌溶解症基础上的精神状态改变:一种罕见的临床表现。
Cureus. 2023 Sep 11;15(9):e45020. doi: 10.7759/cureus.45020. eCollection 2023 Sep.

本文引用的文献

1
Human granulocytic anaplasmosis combined with rhabdomyolysis: a case report.人粒细胞无形体病合并横纹肌溶解症 1 例报告。
BMC Infect Dis. 2021 Nov 25;21(1):1184. doi: 10.1186/s12879-021-06869-z.
2
Ehrlichiosis and Anaplasmosis among Transfusion and Transplant Recipients in the United States.美国血液和器官移植受者中的埃立克体病和无形体病。
Emerg Infect Dis. 2021 Nov;27(11):2768-2775. doi: 10.3201/eid2711.211127.
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Evaluation of a Novel High-Definition PCR Multiplex Assay for Simultaneous Detection of Tick-Borne Pathogens in Human Clinical Specimens.
评估一种新型高通量 PCR 多重检测方法,用于同时检测人类临床标本中的蜱传病原体。
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"Ticking Bomb": The Impact of Climate Change on the Incidence of Lyme Disease.“定时炸弹”:气候变化对莱姆病发病率的影响
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Transfusion-transmitted anaplasmosis from a leukoreduced platelet pool.来自白细胞滤除血小板池的输血传播无形体病。
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Clin Infect Dis. 2007 Jul 15;45(2):199-204. doi: 10.1086/518834. Epub 2007 Jun 5.
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The clinical assessment, treatment, and prevention of lyme disease, human granulocytic anaplasmosis, and babesiosis: clinical practice guidelines by the Infectious Diseases Society of America.莱姆病、人粒细胞无形体病和巴贝斯虫病的临床评估、治疗及预防:美国传染病学会临床实践指南
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Diagnosis and management of tickborne rickettsial diseases: Rocky Mountain spotted fever, ehrlichioses, and anaplasmosis--United States: a practical guide for physicians and other health-care and public health professionals.蜱传立克次体病的诊断与管理:落基山斑疹热、埃立克体病和无形体病——美国:面向医生及其他医疗保健和公共卫生专业人员的实用指南
MMWR Recomm Rep. 2006 Mar 31;55(RR-4):1-27.