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改善居家老年人群药物自我管理的干预措施快速综述。

A rapid review of interventions to improve medicine self-management for older people living at home.

机构信息

Yorkshire Quality and Safety Group, Bradford Teaching Hospitals NHS Foundation Trust, Bradford, United Kingdom.

Medicines Management & Pharmacy Services, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom.

出版信息

Health Expect. 2023 Jun;26(3):945-988. doi: 10.1111/hex.13729. Epub 2023 Mar 14.

Abstract

BACKGROUND

As people age, they are more likely to develop multiple long-term conditions that require complicated medicine regimens. Safely self-managing multiple medicines at home is challenging and how older people can be better supported to do so has not been fully explored.

AIM

This study aimed to identify interventions to improve medicine self-management for older people living at home and the aspects of medicine self-management that they address.

DESIGN

A rapid review was undertaken of publications up to April 2022. Eight databases were searched. Inclusion criteria were as follows: interventions aimed at people 65 years of age or older and their informal carers, living at home. Interventions needed to include at least one component of medicine self-management. Study protocols, conference papers, literature reviews and articles not in the English language were not included. The results from the review were reported through narrative synthesis, underpinned by the Resilient Healthcare theory.

RESULTS

Database searches returned 14,353 results. One hundred and sixty-seven articles were individually appraised (full-text screening) and 33 were included in the review. The majority of interventions identified were educational. In most cases, they aimed to improve older people's adherence and increase their knowledge of medicines. Only very few interventions addressed potential issues with medicine supply. Only a minority of interventions specifically targeted older people with either polypharmacy, multimorbidities or frailty.

CONCLUSION

To date, the emphasis in supporting older people to manage their medicines has been on the ability to adhere to medicine regimens. Most interventions identify and target deficiencies within the patient, rather than preparing patients for problems inherent in the medicine management system. Medicine self-management requires a much wider range of skills than taking medicines as prescribed. Interventions supporting older people to anticipate and respond to problems with their medicines may reduce the risk of harm associated with polypharmacy and may contribute to increased resilience in the system.

PATIENT OR PUBLIC CONTRIBUTION

A patient with lived experience of medicine self-management in older age contributed towards shaping the research question as well as the inclusion and exclusion criteria for this review. She is also the coauthor of this article. A patient advisory group oversaw the study.

摘要

背景

随着人们年龄的增长,他们更容易患上多种需要复杂药物治疗方案的长期疾病。在家中安全地自行管理多种药物具有挑战性,人们尚未充分探索如何更好地支持老年人做到这一点。

目的

本研究旨在确定改善居家老年人生物制剂自我管理的干预措施,以及它们所针对的生物制剂自我管理的各个方面。

设计

对截至 2022 年 4 月的出版物进行了快速审查。搜索了 8 个数据库。纳入标准如下:针对 65 岁及以上人群及其非正规照护者的干预措施,生活在家庭中。干预措施至少应包含一个药物自我管理组成部分。不包括研究方案、会议论文、文献综述和非英文文章。该综述的结果通过叙事综合报告,以弹性医疗保健理论为基础。

结果

数据库搜索返回了 14353 个结果。对 167 篇文章进行了个体评估(全文筛选),并纳入了 33 篇综述。确定的大多数干预措施都是教育性的。在大多数情况下,它们旨在提高老年人的依从性并增加他们对药物的了解。只有极少数干预措施解决了药物供应方面的潜在问题。只有少数干预措施专门针对同时患有多种药物、多种疾病或虚弱的老年人。

结论

迄今为止,支持老年人管理药物的重点一直是坚持药物治疗方案的能力。大多数干预措施识别并针对患者的缺陷,而不是使患者为药物管理系统固有的问题做好准备。药物自我管理需要比按规定服用药物更多的技能。支持老年人预测和应对药物问题的干预措施可能会降低与多种药物治疗相关的伤害风险,并有助于提高系统的弹性。

患者或公众贡献

一位有老年药物自我管理经验的患者为研究问题以及本综述的纳入和排除标准的制定做出了贡献。她也是这篇文章的合著者。一个患者咨询小组监督了这项研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86ee/10154809/080065beb93f/HEX-26--g001.jpg

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