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下腔静脉塌陷指数在预测与中枢神经轴阻滞相关的低血压中的作用:一项前瞻性观察研究。

Role of Inferior Vena Cava Collapsibility Index in the Prediction of Hypotension Associated With Central Neuraxial Block: A Prospective Observational Study.

机构信息

Department of Anaesthesiology, Employees' State Insurance Cooperation Postgraduate Institute of Medical Sciences and Research (ESIC-PGIMSR), New Delhi, India.

出版信息

J Ultrasound Med. 2023 Sep;42(9):1977-1985. doi: 10.1002/jum.16214. Epub 2023 Mar 15.

DOI:10.1002/jum.16214
PMID:36919367
Abstract

BACKGROUND

There are only a few studies on perioperative use of inferior vena cava collapsibility index (IVCCI) to predict hypotension after anesthesia. The study aimed to evaluate IVCCI as predictor of hypotension in patients receiving central neuraxial block (CNB) for elective surgery.

METHOD

One hundred patients of ASA grade I/II, aged 18-60 years undergoing elective surgery under CNB were enrolled. Ultrasound IVC examination was performed preoperatively and the patients were allocated to Group C (Collapsing group: IVCCI ≥50%) or Group NC (Non-Collapsing group: IVCCI <50%). Thereafter, in the operation theatre, the patient was given CNB and observed for development of hypotension. The hypotension was treated with additional fluid bolus (5 mL kg over 10 minutes) and/or vasopressor (mephentramine 6 mg IV). The primary objective was to compare the incidence of hypotension; the secondary objective was to compare the fluid and vasopressor requirement in the Groups C and NC.

RESULT

Six patients were excluded from study due to poor visualization of IVC. The mean IVCCI for Group C (n = 53) was 56.06 ± 4.62% and Group NC (n = 41) was 34.01 ± 8.94%. The incidence of hypotension was 56.60% (20/53) in Group C and 4.87% (2/41) in Group NC (P < .001). The vasopressor and fluid requirement was also statistically significantly higher in Group C compared with Group NC (P < .001).

CONCLUSION

Preoperative ultrasound assessment of IVCCI is useful in predicting hypotension after CNB in patients receiving CNB for elective surgery.

摘要

背景

仅有少数研究探讨围手术期下腔静脉塌陷指数(IVCCI)用于预测全身麻醉后低血压。本研究旨在评估 IVCCI 作为接受中枢神经轴阻滞(CNB)择期手术患者低血压的预测指标。

方法

选择 100 例 ASA 分级 I/II 级、18-60 岁接受 CNB 择期手术的患者。术前进行超声 IVC 检查,并将患者分为 C 组(塌陷组:IVCCI≥50%)或 NC 组(非塌陷组:IVCCI<50%)。此后,在手术室中,患者接受 CNB 并观察低血压的发生情况。低血压采用额外的液体冲击(10 分钟内 5ml/kg)和/或血管加压素(甲麦角林 6mg IV)治疗。主要目标是比较低血压的发生率;次要目标是比较 C 组和 NC 组的液体和血管加压素需求。

结果

由于 IVC 可视化不佳,有 6 例患者被排除在研究之外。C 组(n=53)的平均 IVCCI 为 56.06±4.62%,NC 组(n=41)为 34.01±8.94%。C 组低血压发生率为 56.60%(20/53),NC 组为 4.87%(2/41)(P<.001)。与 NC 组相比,C 组的血管加压素和液体需求也显著更高(P<.001)。

结论

在接受 CNB 择期手术的患者中,术前超声评估 IVCCI 有助于预测 CNB 后低血压。

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