新型冠状病毒感染患者的皮肤表现

Cutaneous Manifestations in Patients with SARS-CoV-2 Infections.

作者信息

Petrakis Vasilios, Panagopoulos Periklis, Terzi Irene, Papazoglou Dimitrios

机构信息

Vasilios Petrakis, MD, Department of Infectious Diseases 2nd University Department of Internal Medicine, University General Hospital of Alexandroupolis, Democritus University of Thrace, Greece;

出版信息

Acta Dermatovenerol Croat. 2022 Dec;30(4):216-219.

PMID:36919387

Abstract

While SARS-CoV-2 is known to cause pneumonia and acute respiratory distress syndrome (ARDS), many extrapulmonary manifestations of COVID-19 have also been observed. Cutaneous manifestations including erythematous rash, urticaria, and chickenpox-like vesicles have been described in patients with SARS-CoV-2. Six patients, two men and four women, in the age group of 50 to 60 years old, hospitalized with SARS-CoV-2 infection confirmed with real-time polymerase chain reaction (real-time PCR) presented cutaneous manifestations. The rash was confluent, spotty, centrifugal, and non-itchy on the head and torso. It was not hemorrhagic, and no crust or blisters were observed. The results of laboratory tests were normal, and the rash disappeared on its own. Several cases of cutaneous manifestations have been reported in patients with SARS-CoV-2 infection. Further studies are needed in order to assess the skin lesions and determine their association with COVID-19.

摘要

虽然已知严重急性呼吸综合征冠状病毒2（SARS-CoV-2）会导致肺炎和急性呼吸窘迫综合征（ARDS），但新型冠状病毒肺炎（COVID-19）的许多肺外表现也已被观察到。感染SARS-CoV-2的患者出现了包括红斑疹、荨麻疹和水痘样水疱在内的皮肤表现。6例年龄在50至60岁之间的患者（2名男性和4名女性）因实时聚合酶链反应（real-time PCR）确诊为SARS-CoV-2感染而住院，出现了皮肤表现。皮疹融合、点状、离心性，头部和躯干无瘙痒感。皮疹无出血，未观察到结痂或水疱。实验室检查结果正常，皮疹自行消退。已有数例SARS-CoV-2感染患者出现皮肤表现的报道。需要进一步研究以评估皮肤病变并确定它们与COVID-19的关联。