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系统性异维A酸单药治疗头皮穿掘性脓肿性毛囊周围炎:病例报告及当前治疗选择综述

Perifolliculitis Capitis Abscedens et Suffodiens Treated with Systemic Isotretinoin Monotherapy: Case Report and Review of Current Therapeutic Options.

作者信息

Rallis Efstathios, Verros Constantinos, Katoulis Alexandros

机构信息

Efstathios Rallis, MD, Department of Biomedical Sciences University of West Attica, Athens, Greece;

出版信息

Acta Dermatovenerol Croat. 2022 Dec;30(4):256-260.

Abstract

Perifolliculitis capitis abscedens et suffodiens (PCAS) is a rare, suppurative dermatosis of the scalp, the etiology of which remains unknown. It is characterized by the development of comedones, perifollicular pustules, firm or fluctuant and itchy or painful nodules and abscesses of the scalp, connected by communicating sinuses that may lead to the formation of scarring and irreversible alopecia. Treatment of PCAS is challenging, often leading to unsatisfactory results. We present a case of a 23-year-old Caucasian man with PCAS who was treated successfully with systemic isotretinoin monotherapy and we review the current therapeutic options.

摘要

穿掘性头部毛囊周围炎(PCAS)是一种罕见的头皮化脓性皮肤病,其病因尚不清楚。它的特征是出现粉刺、毛囊周围脓疱、头皮上坚硬或有波动感且伴有瘙痒或疼痛的结节及脓肿,这些病变通过相通的窦道相连,可能导致瘢痕形成和不可逆的脱发。PCAS的治疗具有挑战性,常常导致不尽人意的结果。我们报告一例23岁患有PCAS的白人男性患者,其通过系统性异维A酸单药治疗获得成功,并对当前的治疗选择进行综述。

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